Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4072685 | 0.77 | MEN1 (0.60) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL27841700 | 0.76 | MEN1 (0.74) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL20467625 | 0.75 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL10012491 | 0.75 | TGM2 (0.70) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL4628679 | 0.74 | KMT2A (0.71) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL4733997 | 0.73 | KMT2A (1.00) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL5657581 | 0.73 | MEN1 (0.70) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL6639523 | 0.73 | CES2 (0.50) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL23497984 | 0.72 | MEN1 (0.49) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL18416955 | 0.71 | MEN1 (0.71) | ALDH1A1MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118256591-A | Cyclic peptide compound having high membrane permeability and library comprising same | 中外制药株式会社 | 2024-06-28 | — | — | CN | disclosed |
| CN-110869544-B | Cyclic peptide compound having high membrane permeability and library comprising same | 中外制药株式会社 | 2024-03-08 | — | — | CN | disclosed |
| US-20230108274-A1 | COMPOSITION FOR TRANSLATION, AND METHOD FOR PRODUCING PEPTIDE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2023-04-06 | — | — | US | disclosed |
| US-20230069218-A1 | METHOD FOR PRODUCING PEPTIDE CONTAINING NON-NATURAL AMINO ACID | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-03-02 | — | — | US | disclosed |
| CN-115667539-A | Translation system with altered genetic code tables | 中外制药株式会社 | 2023-01-31 | — | — | CN | disclosed |
| EP-4026906-A1 | COMPOSITION FOR TRANSLATION, AND METHOD FOR PRODUCING PEPTIDE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-07-13 | — | — | EP | disclosed |
| CN-114641569-A | Composition for translation and method for producing peptide | 中外制药株式会社 | 2022-06-17 | — | — | CN | disclosed |
| CN-113423877-A | Mutant tRNAs for codon expansion | 中外制药株式会社 | 2021-09-21 | — | — | CN | disclosed |
| CN-110869544-A | Cyclic peptide compound having high membrane permeability and library containing same | 中外制药株式会社 | 2020-03-06 | — | — | CN | disclosed |
| US-20200040372-A1 | METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230069218-A1 | METHOD FOR PRODUCING PEPTIDE CONTAINING NON-NATURAL AMINO ACID | MRPL21, RPL41, RPL21 | ALDH1A1 4179/4885MEN1 2956/4885KMT2A 3285/4885 |
| US-20200040372-A1 | METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM | AARS1, NSUN3, RNGTT | ALDH1A1 4757/4885MEN1 2488/4885KMT2A 1543/4885 |
| US-20230108274-A1 | COMPOSITION FOR TRANSLATION, AND METHOD FOR PRODUCING PEPTIDE | NSUN3, TARBP1, NOP2 | ALDH1A1 4768/4885MEN1 3362/4885KMT2A 2391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.