Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13762066 | 0.85 | RAB9A (0.60) | EPHX2RAB9ANPC1LMNAMAPK1 | |
| SCHEMBL21652313 | 0.82 | CTSL (0.66) | EPHX2NR1H4HDAC8HDAC6ALDH1A1 | |
| SCHEMBL19252528 | 0.82 | CA1 (0.61) | EPHX2RAB9ANPC1LMNAMAPK1 | |
| SCHEMBL31474545 | 0.81 | EPHX2 (0.50) | EPHX2NR1H4MEN1KMT2AALDH1A1 | |
| SCHEMBL10451394 | 0.81 | LMNA (0.58) | RAB9ANPC1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL10764773 | 0.80 | CTSL (0.59) | RAB9ANPC1HPGDHDAC1HDAC3 | |
| SCHEMBL17011384 | 0.80 | KDM4E (0.58) | EPHX2LMNAMAPK1HDAC1HDAC3 | |
| SCHEMBL9873510 | 0.80 | CYP1A2 (0.56) | RAB9ANPC1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL26261156 | 0.80 | MEN1 (0.62) | EPHX2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9827345 | 0.80 | CTSL (0.61) | EPHX2RAB9ANPC1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | ME1, MAL2, ME3 | EPHX2 1039/4885RAB9A 4007/4885NPC1 4630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.