Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21653189 | 0.93 | RAB9A (0.43) | ALDH1A1KDM4ECYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21653191 | 0.89 | NAMPT (0.41) | NAMPTALDH1A1KDM4ENPSR1CYP3A4 | |
| SCHEMBL21653197 | 0.85 | RAB9A (0.55) | NAMPTALDH1A1KDM4ENPSR1LMNA | |
| SCHEMBL21653300 | 0.84 | PTPN1 (0.54) | ALDH1A1KDM4ERAB9ASMN1; SMN2HPGD | |
| SCHEMBL21652990 | 0.84 | ALDH1A1 (0.40) | NAMPTALDH1A1KDM4ENPSR1CYP3A4 | |
| SCHEMBL21652982 | 0.83 | ALDH1A1 (0.46) | NAMPTALDH1A1KDM4ENPSR1MEN1 | |
| SCHEMBL21652992 | 0.81 | ALDH1A1 (0.38) | NAMPTALDH1A1KDM4ENPSR1CYP3A4 | |
| SCHEMBL21652984 | 0.78 | ALOX15 (0.48) | ALDH1A1KDM4ERAB9AHPGDALOX15 | |
| SCHEMBL21653202 | 0.76 | CNR2 (0.43) | ALDH1A1KDM4ECYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21653203 | 0.74 | SMN1; SMN2 (0.46) | ALDH1A1KDM4ENPSR1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023657-A1 | PYRIDIN-2-ONE COMPOUNDS USEFUL AS SMARCA2 ANTAGONISTS | Epizyme, Inc. (US) | 2020-01-30 | — | — | WO | disclosed |