Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21653300 | 0.99 | PTPN1 (0.54) | RAB9APTPN1ALDH1A1HPGDKDM4E | |
| SCHEMBL21652982 | 0.89 | ALDH1A1 (0.46) | RAB9AALDH1A1HPGDKDM4ENPSR1 | |
| SCHEMBL21653189 | 0.89 | RAB9A (0.43) | RAB9APTPN1ALDH1A1HPGDKDM4E | |
| SCHEMBL21652984 | 0.86 | ALOX15 (0.48) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL21653188 | 0.85 | NAMPT (0.42) | RAB9AALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL21653191 | 0.84 | NAMPT (0.41) | RAB9AALDH1A1KDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL21653295 | 0.82 | PFKFB3 (0.55) | — | |
| SCHEMBL21652990 | 0.80 | ALDH1A1 (0.40) | RAB9AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL21653202 | 0.79 | CNR2 (0.43) | ALDH1A1KDM4E | |
| SCHEMBL21653203 | 0.77 | SMN1; SMN2 (0.46) | RAB9AALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023657-A1 | PYRIDIN-2-ONE COMPOUNDS USEFUL AS SMARCA2 ANTAGONISTS | Epizyme, Inc. (US) | 2020-01-30 | — | — | WO | disclosed |