Ethyl Acetate

Ethyl Acetate

SCHEMBL2168983

CCCO.CCOC(C)=O.O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Ethyl Acetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.36
CHRM4 known ✓ P08173 1/20 0.36
HTR1A known ✓ P08908 1/20 0.36
CHRM5 known ✓ P08912 1/20 0.36
CHRM1 known ✓ P11229 1/20 0.36
CHRM3 known ✓ P20309 1/20 0.36
ALDH1A1 P00352 6/20 0.74
LMNA P02545 1/20 0.74
HSD17B10 Q99714 1/20 0.74
TSHR P16473 2/20 0.46
ALOX15 P16050 1/20 0.42
MGAM O43451 1/20 0.42
GAA P10253 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
SOAT1 P35610 1/20 0.42
TRPA1 O75762 1/20 0.39
GLO1 Q04760 1/20 0.38
KDM4E B2RXH2 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Acetate SCHEMBL25322004 0.97 ALDH1A1 (0.70) ALDH1A1LMNAHSD17B10TSHRALOX15
Ethyl Acetate SCHEMBL6509098 0.97 ALDH1A1 (0.70) ALDH1A1LMNAHSD17B10TSHRALOX15
Ethyl Acetate SCHEMBL106607 0.97 ALDH1A1 (0.78) ALDH1A1LMNAHSD17B10TSHRALOX15
Ethyl Acetate SCHEMBL7622558 0.95 ALDH1A1 (0.67) ALDH1A1LMNAHSD17B10TSHRALOX15
Ethyl Acetate SCHEMBL29220687 0.95 ALDH1A1 (0.74) ALDH1A1LMNAHSD17B10TSHRALOX15
Ethyl Acetate SCHEMBL28946360 0.91 ALDH1A1 (0.61) ALDH1A1LMNAHSD17B10TSHRALOX15
Ethyl Acetate SCHEMBL22091899 0.91 ALDH1A1 (0.61) ALDH1A1LMNAHSD17B10TSHRALOX15
Hexane SCHEMBL29266096 0.90 ALDH1A1 (0.67) ALDH1A1LMNAHSD17B10TSHRSMN1; SMN2
Cyclohexane SCHEMBL2076849 0.90 ALDH1A1 (0.67) ALDH1A1LMNAHSD17B10TSHRALOX15
Ethyl Acetate SCHEMBL7091348 0.89 ALDH1A1 (0.82) ALDH1A1LMNAHSD17B10TSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9556424-B2 1-deoxy-D-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis GENOPLANTE-VALOR (FR) 2017-01-31 US disclosed
CN-103429612-A 1-deoxy-d-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis GENOPLANTE VALOR 2013-12-04 CN disclosed
US-20130276166-A1 1-DEOXY-D-XYLULOSE 5-PHOSPHATE SYNTHASE ALLELES RESPONSIBLE FOR ENHANCED TERPENE BIOSYNTHESIS GENOPLANTE-VALOR (FR) 2013-10-17 US disclosed
US-8389703-B1 Ribonucleoside analogs with novel hydrogen bonding patterns NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2013-03-05 US disclosed
US-8324177-B2 Triterpene compositions and methods for use thereof RESEARCH DEVELOPMENT FOUNDATION (US) 2012-12-04 US disclosed
US-20110294752-A1 TRITERPENE COMPOSITIONS AND METHODS FOR USE THEREOF RESEARCH DEVELOPMENT FOUNDATION (US) 2011-12-01 US disclosed
EP-1079824-B1 TRITERPENE COMPOSITIONS AND METHODS FOR USE THEREOF RES DEV FOUNDATION (US) 2011-08-31 EP disclosed
US-7985435-B2 Triterpene compositions and methods for use thereof RESEARCH DEVELOPMENT FOUNDATION (US) 2011-07-26 US disclosed
US-20100189824-A1 TRITERPENE COMPOSITIONS AND METHODS FOR USE THEREOF ARNTZEN CHARLES J 2010-07-29 US disclosed
US-7670632-B2 Triterpene compositions and methods for use thereof RESEARCH DEVELOPMENT FOUNDATION (US) 2010-03-02 US disclosed
WO-1995021180-A1 SUBSTITUTED LACTOSE DERIVATIVES AS CELL ADHESION INHIBITORS GLYCOMED INCORPORATED (US) 1995-08-10 WO disclosed
US-4935505-A NUCLEOSIDES; ADENOSINE DEAMINASE INHIBITORS TOWNSEND LEROY B (US) 1990-06-19 US disclosed
EP-0090405-B1 NOVEL AZOLE DINUCLEOTIDE COMPOUNDS AND METHODS FOR THEIR PRODUCTION BRIGHAM YOUNG UNIVERSITY (US) 1986-06-25 EP disclosed
US-4594415-A Viricides ROBINS ROLAND K (US) 1986-06-10 US disclosed
US-4544741-A Azole dinucleotide compounds and methods for their production BRIGHAM YOUNG UNIVERSITY, PROVO, UT., A NONPROFIT CORP. OF UT 1985-10-01 US disclosed
EP-0028083-B1 DERIVATIVES OF CLAVULANIC ACID, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BEECHAM GROUP PLC (GB) 1984-02-08 EP disclosed
EP-0090405-A1 Novel azole dinucleotide compounds and methods for their production BRIGHAM YOUNG UNIVERSITY (US) 1983-10-05 EP disclosed
US-4246408-A Imidazo[1,2-a]-s-triazine ICN PHARMACEUTICALS (US) 1981-01-20 US disclosed
US-4223143-A PYRAZOLO-QUINAZOLIN-ONES, CONTROLLING URIC ACID CONCENTRATION, GOUT, XANTHINE OXIDASE SIEGFRIED AKTIENGESELLSCHAFT (CH) 1980-09-16 US disclosed
US-4093624-A MICROBIOCIDE ICN PHARMACEUTICALS, INC. (US) 1978-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294752-A1 TRITERPENE COMPOSITIONS AND METHODS FOR USE THEREOF OSTC, ACACA, NFATC1 CHRM2 2519/4885CHRM4 2170/4885HTR1A 4795/4885
US-20100189824-A1 TRITERPENE COMPOSITIONS AND METHODS FOR USE THEREOF OSTC, ACACA, NFATC1 CHRM2 2519/4885CHRM4 2170/4885HTR1A 4795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.