Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169266 | 0.87 | HTT (0.41) | TSHRTP53HTTNPSR1SMN1; SMN2 | |
| SCHEMBL3831838 | 0.82 | TSHR (0.56) | TSHRTP53HTTNPSR1SMN1; SMN2 | |
| SCHEMBL2170892 | 0.81 | HTT (0.39) | TP53HTTNPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2170751 | 0.80 | OPRM1 (0.38) | HTTNPSR1SMN1; SMN2PTGIRTRPM8 | |
| SCHEMBL2170336 | 0.73 | PTGIR (0.36) | TP53HTTNPSR1SMN1; SMN2PTGIR | |
| SCHEMBL2171361 | 0.73 | ALDH1A1 (0.40) | ALDH1A1POLB | |
| SCHEMBL2170330 | 0.73 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL2169501 | 0.73 | POLB (0.36) | TP53HTTNPSR1SMN1; SMN2THRB | |
| SCHEMBL30063394 | 0.72 | L3MBTL1 (0.47) | TSHRSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL2172302 | 0.72 | HSD11B1 (0.38) | HTTNPSR1ALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281455-A1 | Phenylpyri(mi)dinylazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281455-A1 | Phenylpyri(mi)dinylazoles | PIR, PIN4, PNN | TSHR 3792/4885TP53 529/4885HTT 2589/4885 |
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | PIR, PIN4, PNN | TSHR 3792/4885TP53 529/4885HTT 2589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.