Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170751 | 0.82 | OPRM1 (0.38) | PTGIRTRPM8GAASMN1; SMN2OPRM1 | |
| SCHEMBL2170892 | 0.78 | HTT (0.39) | PTGIRTRPM8SMN1; SMN2ROCK2HTT | |
| SCHEMBL2169266 | 0.77 | HTT (0.41) | PTGIRTRPM8GAASMN1; SMN2LMNA | |
| SCHEMBL7981765 | 0.74 | PTGIR (0.49) | PTGIRTRPM8GAASMN1; SMN2OPRM1 | |
| SCHEMBL2169727 | 0.73 | TSHR (0.47) | PTGIRTRPM8SMN1; SMN2LMNAHTT | |
| SCHEMBL2169550 | 0.70 | PTGIR (0.41) | PTGIRTRPM8GAASMN1; SMN2ROCK2 | |
| SCHEMBL2171361 | 0.69 | ALDH1A1 (0.40) | GAAROCK2ROCK1POLB | |
| SCHEMBL2169501 | 0.68 | POLB (0.36) | SMN1; SMN2LMNAHTTNPSR1POLB | |
| SCHEMBL30063394 | 0.68 | L3MBTL1 (0.47) | SMN1; SMN2LMNAOPRM1KDM4ECYP1A2 | |
| SCHEMBL2169291 | 0.68 | TRPM8 (0.37) | TRPM8ROCK2LMNAKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | PIR, PIN4, PNN | PTGIR 3056/4885BUB1 1452/4885TRPM8 3578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.