Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171361 | 0.88 | ALDH1A1 (0.40) | ALDH1A1ROCK2ROCK1 | |
| SCHEMBL2169501 | 0.80 | POLB (0.36) | ALDH1A1TDP1MEN1KMT2ACYP3A4 | |
| SCHEMBL2169266 | 0.76 | HTT (0.41) | ALDH1A1TDP1MEN1KMT2ACYP3A4 | |
| SCHEMBL2172302 | 0.75 | HSD11B1 (0.38) | ALDH1A1KMT2A | |
| SCHEMBL2170892 | 0.75 | HTT (0.39) | ALDH1A1TDP1ROCK2MEN1KMT2A | |
| SCHEMBL2170751 | 0.74 | OPRM1 (0.38) | — | |
| SCHEMBL2169727 | 0.73 | TSHR (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2170336 | 0.70 | PTGIR (0.36) | ROCK2ROCK1CYP3A4 | |
| SCHEMBL2171350 | 0.68 | RAB9A (0.41) | ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL7982503 | 0.68 | S100A4 (0.48) | ALDH1A1TDP1MEN1KMT2ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281455-A1 | Phenylpyri(mi)dinylazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281455-A1 | Phenylpyri(mi)dinylazoles | PIR, PIN4, PNN | ALDH1A1 516/4885TDP1 2661/4885ROCK2 4284/4885 |
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | PIR, PIN4, PNN | ALDH1A1 516/4885TDP1 2661/4885ROCK2 4284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.