Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218045 | 0.89 | ALDH1A1 (0.50) | ALDH1A1BCHEACHECA1CA2 | |
| SCHEMBL219017 | 0.86 | ALDH1A1 (0.52) | ALDH1A1BCHEACHECA1CA2 | |
| SCHEMBL7708810 | 0.84 | ALDH1A1 (0.47) | ALDH1A1BCHEACHECA1CA2 | |
| SCHEMBL7578164 | 0.83 | ALDH1A1 (0.47) | ALDH1A1BCHEACHECA1CA2 | |
| SCHEMBL7896349 | 0.81 | ALDH1A1 (0.53) | ALDH1A1BCHEACHECA1CA2 | |
| SCHEMBL7575486 | 0.79 | ALDH1A1 (0.43) | ALDH1A1BCHEACHECA1CA2 | |
| SCHEMBL450158 | 0.78 | ALDH1A1 (0.40) | ALDH1A1HSD11B1HSD17B3MAPTTDP1 | |
| SCHEMBL220568 | 0.76 | ALDH1A1 (0.48) | ALDH1A1BCHEACHECA1CA2 | |
| SCHEMBL7028778 | 0.75 | BCHE (0.53) | ALDH1A1BCHEACHECA1CA2 | |
| SCHEMBL451539 | 0.75 | HSD11B1 (0.53) | ALDH1A1CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088548-B2 | Bottom antireflective coating compositions | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-01-03 | — | — | US | claimed |
| EP-2212273-A2 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS | AZ Electronic Materials USA Corp. (US) | 2010-08-04 | — | — | EP | claimed |
| WO-2009053832-A2 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA CORP. (DE) | 2009-04-30 | — | — | WO | claimed |
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | MERCK PATENT GMBH (DE) | 2009-04-23 | — | — | US | claimed |
| US-8088548-B2 | Bottom antireflective coating compositions | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | MERCK PATENT GMBH (DE) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | SDC2, S100A9, MYH9 | ALDH1A1 3154/4885BCHE 1358/4885ACHE 3212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.