Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK7 | P50613 | 1/20 | 0.41 |
| ▸ | CCNH | P51946 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171618 | 0.90 | FFAR1 (0.50) | L3MBTL1ALDH1A1LMNAESR1LIMK2 | |
| SCHEMBL2169949 | 0.90 | ALDH1A1 (0.58) | L3MBTL1ALDH1A1LMNALIMK2HTT | |
| SCHEMBL2169818 | 0.89 | HSD17B2 (0.49) | ALDH1A1LMNAESR1LIMK2HTT | |
| SCHEMBL2171076 | 0.87 | SLC2A1 (0.46) | ALDH1A1LMNALIMK2HTTSMN1; SMN2 | |
| SCHEMBL2170714 | 0.81 | LMNA (0.45) | ALDH1A1LMNAESR1HTTSMN1; SMN2 | |
| SCHEMBL2170564 | 0.81 | HSD17B3 (0.48) | L3MBTL1ALDH1A1LMNAESR1HTT | |
| SCHEMBL2169880 | 0.79 | HTR6 (0.41) | ALDH1A1LMNALIMK2HTTBRD4 | |
| SCHEMBL2171351 | 0.79 | LMNA (0.52) | ALDH1A1LMNAESR1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5982835 | 0.77 | MEN1 (0.53) | ALDH1A1ESR1HTT | |
| SCHEMBL2550898 | 0.76 | DDB1 (0.36) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346847-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | Suven Life Sciences Limited (IN) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010032258-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-03-25 | — | — | WO | disclosed |