Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CDK7 | P50613 | 1/20 | 0.50 |
| ▸ | CCNH | P51946 | 1/20 | 0.50 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169949 | 0.91 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2HTTLIMK2 | |
| SCHEMBL2169818 | 0.90 | HSD17B2 (0.49) | FFAR1FFAR4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2170713 | 0.90 | L3MBTL1 (0.49) | FFAR1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL2171076 | 0.88 | SLC2A1 (0.46) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL2169824 | 0.80 | ESR1 (0.45) | FFAR1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL2170768 | 0.80 | ESR1 (0.45) | FFAR4ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL2169880 | 0.80 | HTR6 (0.41) | ALDH1A1LMNAMAPTHTTLIMK2 | |
| SCHEMBL2550898 | 0.77 | DDB1 (0.36) | — | |
| SCHEMBL16827668 | 0.76 | NR3C1 (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9480276 | 0.75 | CA12 (0.65) | FFAR1CDK1CCNB1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346847-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | Suven Life Sciences Limited (IN) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010032258-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-03-25 | — | — | WO | disclosed |