Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 5/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | BRD1 | O95696 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171618 | 0.88 | FFAR1 (0.50) | ALDH1A1LMNAHTR6LIMK2HTT | |
| SCHEMBL2169949 | 0.88 | ALDH1A1 (0.58) | ALDH1A1LMNAHTR6LIMK2HTT | |
| SCHEMBL2169818 | 0.87 | HSD17B2 (0.49) | ALDH1A1LMNAHTR6LIMK2HTT | |
| SCHEMBL2170713 | 0.87 | L3MBTL1 (0.49) | ALDH1A1LMNAHTR6LIMK2HTT | |
| SCHEMBL2171609 | 0.82 | HTR6 (0.46) | ALDH1A1LMNAPGRHTR6DRD2 | |
| SCHEMBL2169880 | 0.77 | HTR6 (0.41) | ALDH1A1LMNAHTR6LIMK2HTT | |
| SCHEMBL2236877 | 0.77 | HTR6 (0.40) | ALDH1A1LMNAHTR6DRD2DRD3 | |
| SCHEMBL1546191 | 0.76 | ALOX12 (0.50) | SLC2A1ALDH1A1LMNAPGRHTR6 | |
| SCHEMBL2550898 | 0.75 | DDB1 (0.36) | — | |
| SCHEMBL16827668 | 0.74 | NR3C1 (0.45) | ALDH1A1KCNH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346847-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | Suven Life Sciences Limited (IN) | 2011-07-27 | — | — | EP | claimed |
| WO-2010032258-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-03-25 | — | — | WO | claimed |
| WO-2010032258-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-03-25 | — | — | WO | disclosed |