Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 10/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 8/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | JAK1 | P23458 | 2/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170780 | 0.86 | ALDH1A1 (0.36) | CYP2C8CYP2D6CYP2C9CYP2C19NOS2 | |
| SCHEMBL2169013 | 0.83 | RIPK1 (0.31) | ROCK2CYP2C8CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2170749 | 0.67 | NOS2 (0.33) | ROCK1NOS2 | |
| SCHEMBL659350 | 0.65 | ACACB (0.50) | ROCK2ACACBROCK1NOS2 | |
| SCHEMBL2169288 | 0.64 | CYP2C19 (0.34) | ROCK2CYP2D6CYP2C19ROCK1NOS2 | |
| SCHEMBL509533 | 0.62 | NOS2 (0.42) | CYP2C9NOS2 | |
| SCHEMBL2170620 | 0.62 | NOS2 (0.41) | ROCK2ACACBRIPK1ROCK1NOS2 | |
| SCHEMBL18343348 | 0.61 | SMN1; SMN2 (0.48) | MAPK8 | |
| SCHEMBL6671851 | 0.61 | AKT1 (0.45) | ROCK2CYP2C8CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9911465 | 0.61 | P2RX7 (0.54) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281455-A1 | Phenylpyri(mi)dinylazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281455-A1 | Phenylpyri(mi)dinylazoles | PIR, PIN4, PNN | ROCK2 4284/4885CYP2C8 472/4885CYP2D6 233/4885 |
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | PIR, PIN4, PNN | ROCK2 4284/4885CYP2C8 472/4885CYP2D6 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.