Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 3/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8793075 | 0.98 | AURKA (0.42) | AURKAPARP1DAOMAPKAPK2RPS6KA3 | |
| Hydrochloric Acid SCHEMBL29397868 | 0.98 | AURKA (0.42) | AURKAPARP1DAOMAPKAPK2RPS6KA3 | |
| Trifluoroacetic Acid SCHEMBL34473163 | 0.86 | L3MBTL1 (0.40) | AURKAPARP1DAOFEN1ALDH1A1 | |
| SCHEMBL29623547 | 0.72 | MAPK1 (0.46) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL167394 | 0.72 | MAPK1 (0.46) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL29396007 | 0.71 | ALDH1A1 (0.59) | MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1 | |
| SCHEMBL37862 | 0.71 | ALDH1A1 (0.59) | MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1 | |
| SCHEMBL28647710 | 0.71 | ALDH1A1 (0.40) | AURKADAOMAPKAPK2RPS6KA3CSNK2A1 | |
| SCHEMBL2165024 | 0.71 | AURKA (0.42) | AURKAPARP1DAOFEN1ALDH1A1 | |
| SCHEMBL1416592 | 0.71 | MAPT (0.50) | AURKAPARP1MAPKAPK2RPS6KA3CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175998-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS, LTD. (GB) | 2024-08-29 | — | — | WO | claimed |
| WO-2024175999-A2 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2024-08-29 | — | — | WO | claimed |
| EP-4196480-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND USE THEREOF | Betta Pharmaceuticals Co., Ltd (CN) | 2023-06-21 | — | — | EP | claimed |
| CN-115956080-A | Bicyclic compounds, compositions containing them and their use | 贝达药业股份有限公司 | 2023-04-11 | — | — | CN | claimed |
| EP-1268443-B1 | 2-HYDROXY-MUTILIN CARBAMATE DERIVATIVES FOR ANTIBACTERIAL USE | SMITHKLINE BEECHAM PLC (GB) | 2009-07-29 | — | — | EP | claimed |
| EP-1549655-B1 | SUBSTITUTED BICYCLIC THIOPHENE DERIVATIVES, COMPOSTIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO INC (US) | 2009-01-21 | — | — | EP | claimed |
| WO-2004031189-A1 | PYRIDINO AND PYRIMIDINO PYRAZINONES FOR TREATMENT OF ANXIETY AND DEPRESSION | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2004-04-15 | — | — | WO | claimed |
| US-20030114674-A1 | 2-Hydroxy-mutilin carbamate derivatives for antibacterial use | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-06-19 | — | — | US | claimed |
| EP-1268443-A1 | 2-HYDROXY-MUTILIN CARBAMATE DERIVATIVES FOR ANTIBACTERIAL USE | SmithKline Beecham p.l.c. (GB) | 2003-01-02 | — | — | EP | claimed |
| EP-0736532-B1 | Pyrido(3,2-e)pyrazinones with antiasthmatic activity and process for their preparation | ASTA MEDICA AG (DE) | 2002-05-15 | — | — | EP | claimed |
| WO-2001074788-A1 | 2-HYDROXY-MUTILIN CARBAMATE DERIVATIVES FOR ANTIBACTERIAL USE | SMITHKLINE BEECHAM PLC (GB) | 2001-10-11 | — | — | WO | claimed |
| EP-0992240-A1 | THERAPEUTIC AGENT FOR ERECTION FAILURE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-12 | — | — | EP | claimed |
| EP-0736532-A1 | Pyrido(3,2-e)pyrazinones with antiasthmatic activity and process for their preparation | ASTA Medica Aktiengesellschaft (DE) | 1996-10-09 | — | — | EP | claimed |
| US-20260085048-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | EPIVARIO INC (US) | 2026-03-26 | — | — | US | disclosed |
| EP-4496785-B1 | PESTICIDAL AND HERBICIDAL COMPOUNDS AND METHODS OF USE THEREOF | AG PLENUS LTD (IL) | 2025-12-24 | — | — | EP | disclosed |
| WO-2025245046-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| EP-0736532-A1 | Pyrido(3,2-e)pyrazinones with antiasthmatic activity and process for their preparation | ASTA Medica Aktiengesellschaft (DE) | 1996-10-09 | — | — | EP | disclosed |
| EP-0736532-A1 | Pyrido(3,2-e)pyrazinones with antiasthmatic activity and process for their preparation | ASTA Medica Aktiengesellschaft (DE) | 1996-10-09 | — | — | EP | disclosed |
| EP-0736532-A1 | Pyrido(3,2-e)pyrazinones with antiasthmatic activity and process for their preparation | ASTA Medica Aktiengesellschaft (DE) | 1996-10-09 | — | — | EP | disclosed |
| US-4296114-A | 3,4-Dihydro-3-oxopyrido[2,3-b]-pyrazines, compositions and use thereof | FISONS LIMITED (GB) | 1981-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114674-A1 | 2-Hydroxy-mutilin carbamate derivatives for antibacterial use | MSH6, MSH2, PMS2 | AURKA 4108/4885PARP1 3766/4885DAO 1065/4885 |
| US-20260085048-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | ACSS2, GLS2, ACSL3 | AURKA 2585/4885PARP1 180/4885DAO 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.