Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20476730 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MTNR1AMTNR1BKMT2AKDM4E | |
| SCHEMBL21735541 | 0.84 | GRIK1 (0.54) | ALDH1A1MTNR1AMTNR1BKMT2AKDM4E | |
| SCHEMBL11663572 | 0.84 | ALDH1A1 (0.60) | ALDH1A1MTNR1AMTNR1BKMT2AKDM4E | |
| SCHEMBL21735536 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MTNR1AMTNR1BKMT2AMEN1 | |
| SCHEMBL11664571 | 0.83 | ALDH1A1 (0.58) | ALDH1A1MTNR1AMTNR1BKMT2AKDM4E | |
| SCHEMBL10413633 | 0.83 | ALDH1A1 (0.58) | ALDH1A1MTNR1AMTNR1BKMT2AKDM4E | |
| SCHEMBL4847027 | 0.83 | ALDH1A1 (0.58) | ALDH1A1MTNR1AMTNR1BKMT2AKDM4E | |
| SCHEMBL20476658 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MTNR1AMTNR1BKMT2AKDM4E | |
| SCHEMBL21735538 | 0.82 | MTNR1A (0.64) | ALDH1A1MTNR1AMTNR1BKDM4ESMN1; SMN2 | |
| SCHEMBL26292363 | 0.81 | MTNR1A (0.52) | ALDH1A1MTNR1AMTNR1BTP53GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753387-B2 | Compounds for optically active devices | Johnson & Johnson Surgical Vision, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
| US-11753387-B2 | Compounds for optically active devices | Johnson & Johnson Surgical Vision, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
| EP-3889135-B1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-08-02 | — | — | EP | disclosed |
| EP-3889135-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |
| EP-3583092-B1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2021-05-26 | — | — | EP | disclosed |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| US-11014900-B2 | Hydrophilic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| EP-3583098-B9 | HYDROPHILIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2021-05-12 | — | — | EP | disclosed |
| EP-3583091-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| EP-3583098-B1 | HYDROPHILIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-10-28 | — | — | EP | disclosed |
| US-20200231559-A1 | HYDROPHILIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-07-23 | — | — | US | disclosed |
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | UACA, CRYZ, TRPA1 | ALDH1A1 1851/4885MTNR1A 3327/4885MTNR1B 2622/4885 |
| US-11753387-B2 | Compounds for optically active devices | PDE6C, PDE6A, PDE6D | ALDH1A1 388/4885MTNR1A 1345/4885MTNR1B 837/4885 |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | ALDH1A1 1851/4885MTNR1A 3327/4885MTNR1B 2622/4885 |
| US-20200231559-A1 | HYDROPHILIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | AQP1, AQP3, AQP4 | ALDH1A1 803/4885MTNR1A 2807/4885MTNR1B 1999/4885 |
| US-11014900-B2 | Hydrophilic compounds for optically active devices | AQP1, AQP3, AQP4 | ALDH1A1 803/4885MTNR1A 2807/4885MTNR1B 1999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.