Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4283381 | 0.79 | LTA4H (0.55) | LMNAL3MBTL1SIGMAR1ALDH1A1KDM4E | |
| SCHEMBL334798 | 0.79 | LTA4H (0.60) | LMNACYP2C19CYP1A2KMT2ASIGMAR1 | |
| SCHEMBL4681405 | 0.79 | LTA4H (0.60) | LMNACYP2C19CYP1A2KMT2ASIGMAR1 | |
| SCHEMBL1005557 | 0.79 | LTA4H (0.60) | LMNACYP2C19CYP1A2KMT2ASIGMAR1 | |
| SCHEMBL27802494 | 0.77 | L3MBTL1 (0.52) | LMNAL3MBTL1CYP2C19CYP1A2KMT2A | |
| SCHEMBL6050552 | 0.76 | LMNA (0.54) | LMNAL3MBTL1CYP2C19CYP1A2KMT2A | |
| SCHEMBL4903097 | 0.75 | ALDH1A1 (0.61) | L3MBTL1CYP2C19CYP1A2KMT2ASIGMAR1 | |
| SCHEMBL17485679 | 0.75 | ALDH1A1 (0.61) | L3MBTL1CYP2C19CYP1A2KMT2ASIGMAR1 | |
| SCHEMBL209471 | 0.75 | ALDH1A1 (0.61) | L3MBTL1CYP2C19CYP1A2KMT2ASIGMAR1 | |
| SCHEMBL25640478 | 0.74 | LMNA (0.47) | LMNAL3MBTL1CYP2C19CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | UNIV EMORY (US) | 2023-04-13 | — | — | US | disclosed |
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | EMORY UNIVERSITY | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | LMNA 4470/4885L3MBTL1 4349/4885CYP2C19 4718/4885 |
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | LMNA 4470/4885L3MBTL1 4349/4885CYP2C19 4718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.