Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27780998 | 0.79 | SIGMAR1 (0.51) | LMNAKDM4EALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL21744746 | 0.77 | LMNA (0.51) | L3MBTL1LMNAKDM4EALDH1A1NPSR1 | |
| SCHEMBL27802495 | 0.75 | CHRNB2 (0.51) | KDM4EALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL17485679 | 0.74 | ALDH1A1 (0.61) | L3MBTL1KDM4EALDH1A1NPSR1CYP2C19 | |
| SCHEMBL209471 | 0.74 | ALDH1A1 (0.61) | L3MBTL1KDM4EALDH1A1NPSR1CYP2C19 | |
| SCHEMBL4903097 | 0.74 | ALDH1A1 (0.61) | L3MBTL1KDM4EALDH1A1NPSR1CYP2C19 | |
| SCHEMBL21061629 | 0.73 | L3MBTL1 (0.82) | L3MBTL1LMNAKDM4EALDH1A1NPSR1 | |
| SCHEMBL21061969 | 0.73 | L3MBTL1 (0.82) | L3MBTL1LMNAKDM4EALDH1A1NPSR1 | |
| SCHEMBL3387061 | 0.72 | ALDH1A1 (0.60) | L3MBTL1KDM4EALDH1A1NPSR1CYP2C19 | |
| SCHEMBL3432550 | 0.72 | ALDH1A1 (0.60) | L3MBTL1KDM4EALDH1A1NPSR1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101712655-B | Acetamide derivative and application thereof in pharmacy | YINLIN QIN | 2012-05-23 | — | — | CN | disclosed |
| CN-101712655-A | Acetamide derivative and application thereof in pharmacy | YINLIN QIN | 2010-05-26 | — | — | CN | disclosed |