SCHEMBL21749700

SCHEMBL21749700

Cc1ccc(C(=O)NC[C@@H](NC(=O)OCC(F)(F)F)C(C)(C)C)cc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
RAB9A P51151 2/20 0.44
TDP1 Q9NUW8 1/20 0.43
MLYCD O95822 1/20 0.41
POLB P06746 2/20 0.41
ALDH1A1 P00352 3/20 0.40
LMNA P02545 2/20 0.39
KMT2A Q03164 3/20 0.39
MMP13 P45452 1/20 0.38
MEN1 O00255 2/20 0.38
HPGD P15428 1/20 0.37
EPHX2 P34913 1/20 0.37
PPARG P37231 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18113985 0.86 MLYCD (0.44) NPC1SMN1; SMN2RAB9ATDP1MLYCD
SCHEMBL3810771 0.86 MLYCD (0.44) NPC1SMN1; SMN2RAB9ATDP1MLYCD
SCHEMBL3807941 0.85 KMT2A (0.48) NPC1SMN1; SMN2RAB9ATDP1MLYCD
SCHEMBL30729582 0.81 KMT2A (0.43) NPC1SMN1; SMN2RAB9ATDP1MLYCD
SCHEMBL3810475 0.81 MLYCD (0.45) NPC1SMN1; SMN2RAB9ATDP1MLYCD
SCHEMBL4086683 0.81 SMN1; SMN2 (0.41) NPC1SMN1; SMN2RAB9ATDP1MLYCD
SCHEMBL21141800 0.81 LMNA (0.51) NPC1SMN1; SMN2RAB9ATDP1MLYCD
SCHEMBL13505994 0.81 LMNA (0.51) NPC1SMN1; SMN2RAB9ATDP1MLYCD
SCHEMBL3807531 0.81 NPC1 (0.44) NPC1SMN1; SMN2RAB9ATDP1MLYCD
SCHEMBL3809728 0.79 NPC1 (0.45) NPC1RAB9APOLBALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240065267-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2024-02-29 US claimed
US-12310365-B2 Plant disease control composition and method for controlling plant disease by applying the same MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2025-05-27 US disclosed
US-20240065267-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2024-02-29 US disclosed
US-11805779-B2 Plant disease control composition and method for controlling plant disease by applying the same MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2023-11-07 US disclosed
US-11197479-B2 Use of silthiofam for the treatment of soybean rust GLOBACHEM NV (BE) 2021-12-14 US disclosed
US-20200060279-A1 USE OF SILTHIOFAM FOR THE TREATMENT OF SOYBEAN RUST GLOBACHEM NV (BE) 2020-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240065267-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME SNX1, HAX1, BROX NPC1 461/4885SMN1; SMN2 2501/4885RAB9A 174/4885
US-12310365-B2 Plant disease control composition and method for controlling plant disease by applying the same SNX1, HAX1, BROX NPC1 461/4885SMN1; SMN2 2501/4885RAB9A 174/4885
US-11197479-B2 Use of silthiofam for the treatment of soybean rust TST, LCT, TPST2 NPC1 1660/4885SMN1; SMN2 4190/4885RAB9A 2097/4885
US-20200060279-A1 USE OF SILTHIOFAM FOR THE TREATMENT OF SOYBEAN RUST TST, LCT, TPST2 NPC1 1660/4885SMN1; SMN2 4190/4885RAB9A 2097/4885
US-11805779-B2 Plant disease control composition and method for controlling plant disease by applying the same SNX1, HAX1, BROX NPC1 461/4885SMN1; SMN2 2501/4885RAB9A 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.