Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21758833 | 0.76 | ALDH1A1 (0.38) | — | |
| SCHEMBL21758843 | 0.69 | MEN1 (0.30) | — | |
| SCHEMBL23681163 | 0.69 | ALDH1A1 (0.39) | LOXL2FFAR1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL21758828 | 0.69 | MAOA (0.44) | — | |
| SCHEMBL15922749 | 0.69 | TAS1R3 (0.41) | LOXL2FFAR1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10491649 | 0.68 | TAS1R3 (0.48) | TAS1R3TAS1R1TAS1R2FOLH1 | |
| SCHEMBL21758757 | 0.66 | GSK3B (0.43) | LOXL2 | |
| SCHEMBL21758846 | 0.66 | CYP19A1 (0.41) | — | |
| SCHEMBL21758849 | 0.66 | ALDH1A1 (0.37) | — | |
| SCHEMBL21758758 | 0.66 | TP53 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021221760-A2 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING TO INCLUDE LONG CHAIN CARBON AND CYCLIC AMINO ACIDS | NORTHWESTERN UNIVERSITY (US) | 2021-11-04 | — | — | WO | disclosed |
| WO-2020040840-A2 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING | NORTHWESTERN UNIVERSITY (US) | 2020-02-27 | — | — | WO | disclosed |