Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.65 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | THPO | P40225 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8988146 | 0.93 | ESR1 (0.58) | ESR1ESR2PDCD1CD274HTR3A | |
| SCHEMBL14593355 | 0.89 | ESR1 (0.48) | ESR1ESR2KDM4EALDH1A1 | |
| SCHEMBL1272266 | 0.80 | NR1I2 (0.41) | ESR1ESR2KDM4ELMNAALDH1A1 | |
| SCHEMBL1272903 | 0.80 | NR1I2 (0.41) | ESR1ESR2KDM4ELMNAALDH1A1 | |
| SCHEMBL1273068 | 0.80 | NR1I2 (0.41) | ESR1ESR2KDM4ELMNAALDH1A1 | |
| SCHEMBL3682920 | 0.79 | ESR1 (1.00) | ESR1ESR2PDCD1CD274TAAR1 | |
| SCHEMBL24408977 | 0.78 | PTPN5 (0.43) | ESR1ESR2HIF1AKDM4ELMNA | |
| SCHEMBL24408950 | 0.78 | PTPN5 (0.43) | ESR1ESR2HIF1AKDM4ELMNA | |
| SCHEMBL24397778 | 0.78 | CES2 (0.57) | ESR1ESR2TSHRALDH1A1KIF11 | |
| SCHEMBL21507928 | 0.78 | ESR1 (0.39) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144541-A1 | Process for preparing alpha-halogenated retones | RHODIA CHIMIE (FR) | 2003-07-31 | — | — | US | claimed |
| EP-1250303-A1 | METHOD FOR PREPARING ALPHA-HALOGENATED KETONES | RHODIA CHIMIE (FR) | 2002-10-23 | — | — | EP | claimed |
| WO-2001055067-A1 | METHOD FOR PREPARING ALPHA-HALOGENATED KETONES | RHODIA CHIMIE (FR) | 2001-08-02 | — | — | WO | claimed |
| US-12435185-B2 | Method for producing 1,1,1-trifluoro-2,2-bisarylethane, and 1,1,1-trifluoro-2,2-bisarylethane | CENTRAL GLASS COMPANY, LIMITED (JP) | 2025-10-07 | — | — | US | disclosed |
| US-20230339882-A1 | SHP2 INHIBITOR AND COMPOSITION AND APPLICATION THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2023-10-26 | — | — | US | disclosed |
| EP-4186896-A1 | SHP2 INHIBITOR AND COMPOSITION AND APPLICATION THEREOF | Betta Pharmaceuticals Co., Ltd (CN) | 2023-05-31 | — | — | EP | disclosed |
| US-20220106444-A1 | Method for Producing 1,1,1-Trifluoro-2,2-Bisarylethane, and 1,1,1-Trifluoro-2,2-Bisarylethane | CENTRAL GLASS COMPANY, LIMITED (JP) | 2022-04-07 | — | — | US | disclosed |
| CN-113396137-A | Method for producing 1,1, 1-trifluoro-2, 2-bisarylethane, and 1,1, 1-trifluoro-2, 2-bisarylethane | 中央硝子株式会社 | 2021-09-14 | — | — | CN | disclosed |
| WO-2020162408-A1 | METHOD FOR PRODUCING 1,1,1-TRIFLUORO-2,2-BISARYLETHANE, AND 1,1,1-TRIFLUORO-2,2-BISARYLETHANE | セントラル硝子株式会社 | 2020-08-13 | — | — | WO | disclosed |
| US-20180085359-A1 | USE OF CHELATORS OF DIVALENT CATIONS TO PROMOTE NERVE REGENERATION | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2018-03-29 | — | — | US | disclosed |
| US-20180085359-A1 | USE OF CHELATORS OF DIVALENT CATIONS TO PROMOTE NERVE REGENERATION | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2018-03-29 | — | — | US | disclosed |
| US-20030144541-A1 | Process for preparing alpha-halogenated retones | RHODIA CHIMIE (FR) | 2003-07-31 | — | — | US | disclosed |
| US-20030144524-A1 | With an aromatic derivative carrying at least one hydroxyl functional group, wherein the electron-withdrawing group present on the carbonyl compound is selected from fluoroalkyl derivatives, esters, including orthoesters, and nitriles and | RHODIA CHIMIE, FRANCE | 2003-07-31 | — | — | US | disclosed |
| US-6541674-B2 | Electron-withdrawing group present on carbonyl compound is selected from fluoroalkyl derivatives, esters, including orthoesters, and nitrites and condensation is carried out in basic medium | RHODIA CHIMIE (FR) | 2003-04-01 | — | — | US | disclosed |
| EP-1250303-A1 | METHOD FOR PREPARING ALPHA-HALOGENATED KETONES | RHODIA CHIMIE (FR) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001055067-A1 | METHOD FOR PREPARING ALPHA-HALOGENATED KETONES | RHODIA CHIMIE (FR) | 2001-08-02 | — | — | WO | disclosed |
| US-20010004670-A1 | Process for the condensation of a carbonyl compound with an aromatic derivative in a basic medium | RHODIA CHIMIE (FR) | 2001-06-21 | — | — | US | disclosed |
| EP-1100785-A1 | SUBSTITUTED CYCLOHEXYLAMINOPYRIMIDINES | Aventis CropScience GmbH (DE) | 2001-05-23 | — | — | EP | disclosed |
| US-6197729-B1 | COMBATING PEST WHICH COMPRISES APPLYING TO PEST OR ITS LOCUS PESTICIDAL CYCLOHEXYLAMINOPYRIMIDINNE COMPOUND | HOECHST SCHERING AGREVO (DE) | 2001-03-06 | — | — | US | disclosed |
| WO-2000007998-A1 | SUBSTITUTED CYCLOHEXYLAMINOPYRIMIDINES | AVENTIS CROPSCIENCE GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220106444-A1 | Method for Producing 1,1,1-Trifluoro-2,2-Bisarylethane, and 1,1,1-Trifluoro-2,2-Bisarylethane | NAF1, FXR1, AFF1 | ESR1 4737/4885ESR2 3744/4885PDCD1 3760/4885 |
| US-20180085359-A1 | USE OF CHELATORS OF DIVALENT CATIONS TO PROMOTE NERVE REGENERATION | GAP43, NGF, SMN1; SMN2 | ESR1 4776/4885ESR2 4485/4885PDCD1 2828/4885 |
| US-12435185-B2 | Method for producing 1,1,1-trifluoro-2,2-bisarylethane, and 1,1,1-trifluoro-2,2-bisarylethane | NAF1, FXR1, AFF1 | ESR1 4737/4885ESR2 3744/4885PDCD1 3760/4885 |
| US-20010004670-A1 | Process for the condensation of a carbonyl compound with an aromatic derivative in a basic medium | NCAPH, ODC1, NCAPD2 | ESR1 1877/4885ESR2 1668/4885PDCD1 3738/4885 |
| US-20030144524-A1 | With an aromatic derivative carrying at least one hydroxyl functional group, wherein the electron-withdrawing group present on the carbonyl compound is selected from fluoroalkyl derivatives, esters, including orthoesters, and nitriles and | ECE2, HCN4, ETV6 | ESR1 107/4885ESR2 194/4885PDCD1 3089/4885 |
| US-20030144541-A1 | Process for preparing alpha-halogenated retones | ADH1A, ADH1C, RER1 | ESR1 1300/4885ESR2 765/4885PDCD1 3152/4885 |
| US-20230339882-A1 | SHP2 INHIBITOR AND COMPOSITION AND APPLICATION THEREOF | PTPRF, PTPRCAP, PTPRJ | ESR1 3361/4885ESR2 1514/4885PDCD1 1454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.