Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.33 |
| ▸ | HTR2A | P28223 | 8/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21756947 | 0.74 | SLC6A4 (0.32) | SLC6A4KCNH2HTR2ASLC6A2MCL1 | |
| SCHEMBL21756928 | 0.72 | SLC6A4 (0.39) | SLC6A4KCNH2HTR2ASLC6A2 | |
| SCHEMBL25922204 | 0.67 | DHFR (0.35) | — | |
| SCHEMBL14612634 | 0.66 | TTR (0.41) | MCL1 | |
| SCHEMBL24059231 | 0.63 | ALDH1A1 (0.38) | SLC6A4KCNH2HTR2ASLC6A2 | |
| SCHEMBL8337555 | 0.63 | DPP4 (0.42) | SLC6A4KCNH2HTR2ASLC6A2MCL1 | |
| SCHEMBL21756934 | 0.63 | SLC6A4 (0.31) | SLC6A4 | |
| SCHEMBL22011782 | 0.63 | HMGCR (0.34) | — | |
| SCHEMBL30740928 | 0.63 | SLC6A4 (0.43) | SLC6A4KCNH2HTR2ASLC6A2MCL1 | |
| SCHEMBL13452521 | 0.63 | SLC6A4 (0.41) | SLC6A4KCNH2HTR2ASLC6A2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039094-A1 | PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERATIVE ACTIVITY | Xeniopro GmbH (DE) | 2020-02-27 | — | — | WO | disclosed |