Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90B1 | P14625 | 2/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769236 | 0.92 | HSP90B1 (0.44) | HSP90B1TRAP1FAAHPDK2ALDH1A1 | |
| SCHEMBL21769483 | 0.87 | TRAP1 (0.43) | HSP90B1TRAP1PDK2KDM4EALDH1A1 | |
| SCHEMBL21769498 | 0.86 | HSD17B10 (0.40) | HSP90B1TRAP1FAAHKDM4EALDH1A1 | |
| SCHEMBL21769528 | 0.86 | ALDH1A1 (0.47) | KDM4EALDH1A1SMN1; SMN2FNTAFNTB | |
| SCHEMBL21769408 | 0.85 | MAPT (0.41) | KDM4EFNTAFNTB | |
| SCHEMBL21769409 | 0.85 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2FNTAFNTB | |
| SCHEMBL21769254 | 0.84 | THRA (0.39) | HSP90B1TRAP1KDM4EFNTAFNTB | |
| SCHEMBL21769530 | 0.82 | ESR1 (0.44) | ALDH1A1SMN1; SMN2FNTAFNTB | |
| SCHEMBL21769508 | 0.82 | FNTA (0.37) | KDM4ESMN1; SMN2FNTAFNTB | |
| SCHEMBL21769462 | 0.81 | ALDH1A1 (0.48) | KDM4EALDH1A1SMN1; SMN2FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200064334-A1 | Dock Derived Compound against Laminin Receptor (37 LR) and Uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200064334-A1 | Dock Derived Compound against Laminin Receptor (37 LR) and Uses thereof | ILK, LRRC47, RPL37 | HSP90B1 437/4885TRAP1 200/4885FAAH 4803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.