Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769573 | 0.91 | POLB (0.39) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL17923453 | 0.90 | MAPT (0.35) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL21769855 | 0.90 | MEN1 (0.39) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL17923449 | 0.89 | SMN1; SMN2 (0.36) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL21769740 | 0.89 | L3MBTL1 (0.33) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL17923455 | 0.88 | MAPT (0.37) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL21769874 | 0.88 | MAPT (0.38) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL21769731 | 0.87 | KMT2A (0.40) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL21769885 | 0.86 | POLB (0.37) | ALDH1A1GAAMAPTTDP1POLB | |
| SCHEMBL6011837 | 0.85 | ALDH1A1 (0.36) | KMT2AMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |