Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21773974 | 0.84 | HPGD (0.52) | MT-CO2LMNAHPGDALDH1A1MEN1 | |
| SCHEMBL21773977 | 0.78 | MEN1 (0.56) | LMNAHPGDTRPV1ALDH1A1CYP1A2 | |
| SCHEMBL21773971 | 0.78 | CA1 (0.57) | CYP1A2CYP3A4CYP2C19KMT2AGAA | |
| SCHEMBL14698338 | 0.77 | APEX1 (0.59) | LMNAHPGDTRPV1ALDH1A1CYP1A2 | |
| SCHEMBL21773986 | 0.77 | LMNA (0.59) | LMNAHPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30520585 | 0.76 | APEX1 (0.58) | LMNAHPGDTRPV1ALDH1A1CYP1A2 | |
| SCHEMBL21623922 | 0.76 | APEX1 (0.58) | LMNAHPGDTRPV1ALDH1A1CYP1A2 | |
| SCHEMBL21773973 | 0.76 | MT-CO2 (0.50) | MT-CO2LMNAHPGDMEN1MAPT | |
| SCHEMBL1031773 | 0.76 | TRPV1 (0.59) | LMNAHPGDTRPV1ALDH1A1CYP1A2 | |
| SCHEMBL3862031 | 0.74 | ALOX5 (0.64) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11999677-B2 | Benzylamino-oxoethyl benzamide analogs and methods of use | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2024-06-04 | — | — | US | disclosed |
| US-20220162157-A1 | BENZYLAMINO-OXOETHYL BENZAMIDE ANALOGS AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2022-05-26 | — | — | US | disclosed |
| US-20200071264-A1 | BENZYLAMINO-OXOETHYL BENZAMIDE ANALOGS AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162157-A1 | BENZYLAMINO-OXOETHYL BENZAMIDE ANALOGS AND METHODS OF USE | BAD, ATP2A1, IAPP | MT-CO2 3672/4885LMNA 1233/4885HPGD 1794/4885 |
| US-20200071264-A1 | BENZYLAMINO-OXOETHYL BENZAMIDE ANALOGS AND METHODS OF USE | BAD, ATP2A1, IAPP | MT-CO2 3672/4885LMNA 1233/4885HPGD 1794/4885 |
| US-11999677-B2 | Benzylamino-oxoethyl benzamide analogs and methods of use | BAD, ATP2A1, IAPP | MT-CO2 3672/4885LMNA 1233/4885HPGD 1794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.