Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418865 | 0.79 | TDP1 (0.41) | TDP1ALDH1A1LMNACYP3A4THRB | |
| SCHEMBL10024341 | 0.74 | TDP1 (0.55) | TDP1ALDH1A1LMNACYP3A4THRB | |
| SCHEMBL11444008 | 0.72 | TDP1 (0.35) | TDP1ALDH1A1LMNACYP3A4THRB | |
| SCHEMBL5442950 | 0.71 | ALDH1A1 (0.30) | ALDH1A1ALOX15ALOX12HSD17B10 | |
| SCHEMBL27304066 | 0.69 | ROCK2 (0.36) | TDP1ALDH1A1LMNAALOX15L3MBTL1 | |
| SCHEMBL18358107 | 0.69 | TRPM8 (0.39) | TDP1ALDH1A1LMNARECQLL3MBTL1 | |
| SCHEMBL11408555 | 0.68 | RAPGEF4 (0.39) | TDP1ALDH1A1LMNACYP3A4THRB | |
| SCHEMBL14446457 | 0.66 | GABRA1 (0.38) | TDP1ALDH1A1LMNACYP3A4TSHR | |
| SCHEMBL18998887 | 0.65 | TDP1 (0.46) | TDP1ALDH1A1LMNACYP3A4THRB | |
| SCHEMBL20763402 | 0.65 | TDP1 (0.46) | TDP1ALDH1A1LMNACYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3245213-B1 | BENZODIAZEPINE DIMERS, CONJUGATES THEREOF, AND METHODS OF MAKING AND USING | BRISTOL MYERS SQUIBB CO (US) | 2020-03-04 | — | — | EP | disclosed |