SCHEMBL218264

SCHEMBL218264

C=C(C)C(=O)Nc1ccccc1N=Nc1ccc([N+](=O)[O-])c(O)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 7/20 0.41
▸ KMT2A Q03164 7/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ GRIN2D O15399 1/20 0.38
▸ GRIN3B O60391 1/20 0.38
▸ GRIN1 Q05586 1/20 0.38
▸ GRIN2A Q12879 1/20 0.38
▸ GRIN2B Q13224 1/20 0.38
▸ GRIN2C Q14957 1/20 0.38
▸ GRIN3A Q8TCU5 1/20 0.38
▸ SIGMAR1 Q99720 1/20 0.38
▸ KCNMA1 Q12791 2/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ HTT P42858 2/20 0.36
▸ PDE7A Q13946 1/20 0.36
▸ CXCR1 P25024 1/20 0.36
▸ CXCR2 P25025 1/20 0.36
▸ CRHBP P24387 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL219154 0.81 KMT2A (0.46) MEN1KMT2ANPC1TDP1L3MBTL1
SCHEMBL4651722 0.81 KMT2A (0.46) MEN1KMT2ANPC1TDP1L3MBTL1
SCHEMBL217821 0.79 ATIC (0.39) MEN1KMT2ATDP1L3MBTL1MAPT
SCHEMBL9450739 0.78 NPC1 (0.48) NPC1RAB9AGRIN2DGRIN3BGRIN1
SCHEMBL14690094 0.78 NPC1 (0.48) NPC1RAB9AGRIN2DGRIN3BGRIN1
SCHEMBL4000024 0.77 CHRM1 (0.50) MEN1KMT2ANPC1RAB9ASIGMAR1
SCHEMBL14690050 0.76 MAPT (0.51) MEN1KMT2ANPC1RAB9ATDP1
SCHEMBL217397 0.76 CA12 (0.43) MEN1KMT2ARAB9AMAPTLMNA
SCHEMBL4651757 0.76 CA12 (0.43) MEN1KMT2ARAB9AMAPTLMNA
SCHEMBL516294 0.74 KMT2A (0.61) MEN1KMT2ANPC1RAB9AKCNMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088548-B2 Bottom antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-01-03 — — US disclosed
EP-2212273-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2010-08-04 — — EP disclosed
US-7553905-B2 Anti-reflective coatings AZ ELECTRONIC MATERIALS USA CORP. (US) 2009-06-30 — — US disclosed
WO-2009053832-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2009-04-30 — — WO disclosed
US-20090104559-A1 Bottom Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2009-04-23 — — US disclosed
EP-1966255-A1 ANTI-REFLECTIVE COATINGS AZ Electronic Materials USA Corp. (US) 2008-09-10 — — EP disclosed
WO-2007052132-A1 ANTI-REFLECTIVE COATINGS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2007-05-10 — — WO disclosed
US-20070099108-A1 Anti-reflective coatings MERCK PATENT GMBH (DE) 2007-05-03 — — US disclosed
US-20060063105-A1 Negative-working photoimageable bottom antireflective coating OBERLANDER JOSEPH E 2006-03-23 — — US disclosed
EP-1466214-A2 NEGATIVE-WORKING PHOTOIMABEABLE BOTTOM ANTIREFLECTIVE COATING AZ Electronic Materials USA Corp. (US) 2004-10-13 — — EP disclosed
US-20030215736-A1 Negative-working photoimageable bottom antireflective coating AZ ELECTRONIC MATERIALS USA CORP. 2003-11-20 — — US disclosed
WO-2003058345-A2 NEGATIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING CLARIANT INTERNATIONAL LTD (CH) 2003-07-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104559-A1 Bottom Antireflective Coating Compositions SDC2, S100A9, MYH9 MEN1 883/4885KMT2A 1852/4885NPC1 369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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