SCHEMBL816271

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL217953	0.80	ALDH1A1 (0.44)	ALDH1A1HSD17B10HIF1ATSHRCYP2A6
	SCHEMBL814891	0.76	ALDH1A1 (0.41)	ALDH1A1HSD17B10HIF1ATSHRTDP1
	SCHEMBL4856624	0.72	ALDH1A1 (1.00)	ALDH1A1HSD17B10HIF1ACYP1B1TSHR
	Dibenz[A,H]Anthracene SCHEMBL29392838	0.72	ALDH1A1 (1.00)	ALDH1A1HSD17B10HIF1ACYP1B1TSHR
	Dibenz[A,H]Anthracene SCHEMBL156100	0.72	ALDH1A1 (1.00)	ALDH1A1HSD17B10HIF1ACYP1B1TSHR
	Dibenz[A,H]Anthracene SCHEMBL29777008	0.72	ALDH1A1 (1.00)	ALDH1A1HSD17B10HIF1ACYP1B1TSHR
	SCHEMBL214275	0.71	DNMT1 (0.46)	ALDH1A1HSD17B10HIF1ACYP1B1TSHR
	SCHEMBL145793	0.71	ALDH1A1 (0.44)	ALDH1A1HSD17B10HIF1ACYP1B1TSHR
	SCHEMBL815144	0.70	HPRT1 (0.52)	ALDH1A1HSD17B10HIF1ACYP1B1TSHR
	SCHEMBL4846533	0.70	ALDH1A1 (0.83)	ALDH1A1HSD17B10HIF1ACYP1B1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.