Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | COMT | P21964 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31680549 | 0.87 | MMP2 (0.54) | MMP2MMP9COMTMMP8MMP13 | |
| SCHEMBL15094744 | 0.86 | KMT2A (0.49) | MMP2MMP9COMTMMP8MMP13 | |
| SCHEMBL21067860 | 0.86 | KMT2A (0.58) | NPC1RAB9ASMN1; SMN2HPGDKCNK3 | |
| SCHEMBL9589707 | 0.84 | NPC1 (0.49) | MAOAMAOBMMP2MMP9MMP8 | |
| SCHEMBL15094666 | 0.83 | RAB9A (0.54) | NPC1RAB9ASMN1; SMN2TSHRMAPT | |
| SCHEMBL15094758 | 0.82 | RXFP1 (0.48) | MAOAMAOB | |
| SCHEMBL1249670 | 0.81 | NPC1 (0.55) | MMP2MMP9COMTMMP8MMP13 | |
| SCHEMBL15094761 | 0.81 | BRAF (0.50) | MAOAKDM1AMAOBMMP2MMP9 | |
| SCHEMBL16341283 | 0.80 | MAOA (0.53) | MAOAMAOBMMP2MMP9COMT | |
| SCHEMBL22167182 | 0.80 | MGLL (0.54) | ALDH1A1MAPTKMT2AMEN1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10604493-B2 | Compositions, methods of use, and methods of treatment | UNIVERSITY OF SOUTH FLORIDA (US) | 2020-03-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10604493-B2 | Compositions, methods of use, and methods of treatment | LIPA, LCT, GAA | MAOA 104/4885KDM1A 1016/4885MAOB 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.