Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | GAA | P10253 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10734949 | 0.98 | ALDH1A1 (0.55) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL69313 | 0.81 | GAA (0.71) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL9806950 | 0.81 | CISD2 (0.57) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL4264510 | 0.80 | ALDH1A1 (0.49) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL13748344 | 0.80 | SMN1; SMN2 (0.49) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL11581298 | 0.79 | GAA (0.55) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL27191784 | 0.79 | GAA (0.55) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL10891632 | 0.78 | CISD2 (0.55) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL166884 | 0.78 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTHPGDMEN1 | |
| SCHEMBL19296281 | 0.78 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624023-B2 | Sulfonylurea derivatives and uses thereof | NodThera Limited (GB) | 2026-05-12 | — | — | US | disclosed |
| EP-3983407-B1 | SULFONYLUREA DERIVATIVES AND USES THEREOF | NODTHERA LTD (GB) | 2025-11-12 | — | — | EP | disclosed |
| US-12421243-B2 | Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms | PRINTNET KERESKEDELMI ÉS SZOLGÁLTATÓ KFT. (HU) | 2025-09-23 | — | — | US | disclosed |
| CN-114222739-B | Sulfonylurea derivatives and their use | 诺瑟拉有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-112334191-B | Pharmaceutically effective compounds for selectively inhibiting myosin 2 isoforms | 普林特商业服务有限公司 | 2024-12-10 | — | — | CN | disclosed |
| US-20240270752-A1 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | EÖTVÖS LORÁND TUDOMÁNYEGYETEM (HU) | 2024-08-15 | — | — | US | disclosed |
| CN-117924285-A | Pharmaceutically effective compounds for selectively inhibiting myosin 2 isoforms | 普林特商业服务有限公司 | 2024-04-26 | — | — | CN | disclosed |
| US-11845758-B2 | Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms | PRINTNET KERESKEDELMI ÉS SZOLGÁLTATÓ KFT. (HU) | 2023-12-19 | — | — | US | disclosed |
| EP-4276102-A2 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | Printnet Kereskedelmi és Szolgáltató Kft. (HU) | 2023-11-15 | — | — | EP | disclosed |
| US-20230339959-A1 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | EÖTVÖS LORÁND TUDOMÁNYEGYETEM (HU) | 2023-10-26 | — | — | US | disclosed |
| EP-0588299-A2 | 1,2,4-Oxadiazolyl- or 1,2,4-thiadiazolyl-biphenyl derivatives as angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5229382-A | Treating disorders of the central nervous system including psychosis, acute mania, anxiety, or schizophrenia | LILLY INDUSTRIES LIMITED (GB) | 1993-07-20 | — | — | US | disclosed |
| EP-0454436-A1 | Pharmaceutical compounds | LILLY INDUSTRIES LIMITED (GB) | 1991-10-30 | — | — | EP | disclosed |
| US-4692461-A | PLANT PROTECTION | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |
| US-4222946-A | ANTIALLERGEN, HYPERSENSITIVITY | LILLY INDUSTRIES, LIMITED (GB) | 1980-09-16 | — | — | US | disclosed |
| US-4187232-A | ANTIALLERGENS | LILLY INDUSTRIES LIMITED (GB) | 1980-02-05 | — | — | US | disclosed |
| US-4172831-A | CENTRAL NERVOUS SYSTEM | LILLY INDUSTRIES LIMITED (GB) | 1979-10-30 | — | — | US | disclosed |
| US-4115568-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |
| US-4115574-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |
| US-3932642-A | BACTERICIDES, FUNGICIDES, TRICHOMONOCIDES | BOEHRINGER INGELHEIM GMBH (DT) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11845758-B2 | Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms | MYH2, MYLK2, MYO1B | ALDH1A1 2854/4885GAA 645/4885MAPT 99/4885 |
| US-20240270752-A1 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | MYH2, MYLK2, MYO1B | ALDH1A1 2854/4885GAA 645/4885MAPT 99/4885 |
| US-12421243-B2 | Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms | MYH2, MYLK2, MYO1B | ALDH1A1 2854/4885GAA 645/4885MAPT 99/4885 |
| US-12624023-B2 | Sulfonylurea derivatives and uses thereof | PYCARD, NOD1, NLRP3 | ALDH1A1 561/4885GAA 4468/4885MAPT 4223/4885 |
| US-20230339959-A1 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | MYH2, MYLK2, MYO1B | ALDH1A1 2854/4885GAA 645/4885MAPT 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.