Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29383170 | 1.00 | RAB9A (0.41) | RAB9ANPC1PAX8NPBWR1MCHR1 | |
| SCHEMBL18528469 | 0.86 | NPC1 (0.40) | RAB9ANPC1PAX8NPBWR1MCHR1 | |
| SCHEMBL30576375 | 0.86 | NPC1 (0.40) | RAB9ANPC1PAX8NPBWR1MCHR1 | |
| SCHEMBL21835458 | 0.85 | HSD11B1 (0.38) | RAB9ANPC1NPBWR1HSD11B1SMN1; SMN2 | |
| SCHEMBL29383185 | 0.85 | HSD11B1 (0.38) | RAB9ANPC1NPBWR1HSD11B1SMN1; SMN2 | |
| SCHEMBL29382816 | 0.83 | NPBWR1 (0.41) | RAB9ANPC1NPBWR1MCHR1MAPT | |
| SCHEMBL21835495 | 0.83 | NPBWR1 (0.41) | RAB9ANPC1NPBWR1MCHR1MAPT | |
| SCHEMBL25202984 | 0.78 | HPGD (0.38) | RAB9ANPC1MAPTHSD11B1SMN1; SMN2 | |
| SCHEMBL21835475 | 0.75 | MAPT (0.45) | RAB9ANPC1NPBWR1MAPTHSD11B1 | |
| SCHEMBL29384915 | 0.75 | MAPT (0.45) | RAB9ANPC1NPBWR1MAPTHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856723-A1 | PYRIDAZINONE HERBICIDES AND PYRIDAZINONE INTERMEDIATES USED TO PREPARE A HERBICIDE | FMC Corporation (US) | 2021-08-04 | — | — | EP | disclosed |
| CN-113166075-A | Pyridazinone herbicides and pyridazinone intermediates for the preparation thereof | FMC公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020069057-A1 | PYRIDAZINONE HERBICIDES AND PYRIDAZINONE INTERMEDIATES USED TO PREPARE A HERBICIDE | FMC CORPORATION (US) | 2020-04-02 | — | — | WO | disclosed |