Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18528469 | 1.00 | NPC1 (0.40) | NPC1RAB9APAX8NPBWR1MCHR1 | |
| SCHEMBL30576368 | 0.87 | MMP1 (0.36) | NPSR1ALDH1A1MAPTKAT2BBRD9 | |
| SCHEMBL18528470 | 0.87 | MMP1 (0.36) | NPSR1ALDH1A1MAPTKAT2BBRD9 | |
| SCHEMBL21835554 | 0.86 | RAB9A (0.41) | NPC1RAB9APAX8NPBWR1MCHR1 | |
| SCHEMBL29383170 | 0.86 | RAB9A (0.41) | NPC1RAB9APAX8NPBWR1MCHR1 | |
| SCHEMBL20522633 | 0.72 | ALDH1A1 (0.41) | NPBWR1NPSR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21835458 | 0.70 | HSD11B1 (0.38) | NPC1RAB9ANPBWR1NPSR1ALDH1A1 | |
| SCHEMBL29383185 | 0.70 | HSD11B1 (0.38) | NPC1RAB9ANPBWR1NPSR1ALDH1A1 | |
| SCHEMBL31001028 | 0.70 | CYP1A2 (0.52) | RAB9ANPSR1ALDH1A1MAPTHPGD | |
| SCHEMBL21835495 | 0.69 | NPBWR1 (0.41) | NPC1RAB9ANPBWR1MCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111018790-B | Pyridazinone herbicides | FMC公司 | 2023-09-19 | — | — | CN | disclosed |