Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576375 | 1.00 | NPC1 (0.40) | NPC1RAB9APAX8NPBWR1MCHR1 | |
| SCHEMBL30576368 | 0.87 | MMP1 (0.36) | NPSR1ALDH1A1MAPTKAT2BBRD9 | |
| SCHEMBL18528470 | 0.87 | MMP1 (0.36) | NPSR1ALDH1A1MAPTKAT2BBRD9 | |
| SCHEMBL21835554 | 0.86 | RAB9A (0.41) | NPC1RAB9APAX8NPBWR1MCHR1 | |
| SCHEMBL29383170 | 0.86 | RAB9A (0.41) | NPC1RAB9APAX8NPBWR1MCHR1 | |
| SCHEMBL20522633 | 0.72 | ALDH1A1 (0.41) | NPBWR1NPSR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21835458 | 0.70 | HSD11B1 (0.38) | NPC1RAB9ANPBWR1NPSR1ALDH1A1 | |
| SCHEMBL29383185 | 0.70 | HSD11B1 (0.38) | NPC1RAB9ANPBWR1NPSR1ALDH1A1 | |
| SCHEMBL31001028 | 0.70 | CYP1A2 (0.52) | RAB9ANPSR1ALDH1A1MAPTHPGD | |
| SCHEMBL21835495 | 0.69 | NPBWR1 (0.41) | NPC1RAB9ANPBWR1MCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111018790-B | Pyridazinone herbicides | FMC公司 | 2023-09-19 | — | — | CN | disclosed |
| EP-3865480-A1 | HYDRAZINE DERIVATIVES | FMC Corporation (US) | 2021-08-18 | — | — | EP | disclosed |
| EP-3137456-B1 | PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-06-02 | — | — | EP | disclosed |
| CN-111018790-A | Pyridazinone herbicides | FMC公司 | 2020-04-17 | — | — | CN | disclosed |
| US-10597388-B2 | Pyridazinone herbicides | FMC CORPORATION (US) | 2020-03-24 | — | — | US | disclosed |
| CN-106458926-B | Pyridazinone herbicides | FMC公司 | 2020-01-03 | — | — | CN | disclosed |
| US-20190016712-A1 | PYRIDAZINONE HERBICIDES | FMC CORPORATION | 2019-01-17 | — | — | US | disclosed |
| US-10118917-B2 | Pyridazinone herbicides | FMC CORPORATION | 2018-11-06 | — | — | US | disclosed |
| US-20170050953-A1 | PYRIDAZINONE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190016712-A1 | PYRIDAZINONE HERBICIDES | CBR3, NOX5, NR5A2 | NPC1 4731/4885RAB9A 3274/4885PAX8 2199/4885 |
| US-20170050953-A1 | PYRIDAZINONE HERBICIDES | CBR3, NOX5, NR5A2 | NPC1 4731/4885RAB9A 3274/4885PAX8 2199/4885 |
| US-10118917-B2 | Pyridazinone herbicides | CBR3, NOX5, NR5A2 | NPC1 4731/4885RAB9A 3274/4885PAX8 2199/4885 |
| US-10597388-B2 | Pyridazinone herbicides | CBR3, NOX5, NR5A2 | NPC1 4731/4885RAB9A 3274/4885PAX8 2199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.