SCHEMBL218365

SCHEMBL218365

COc1[c]c2c(cc1OC)-c1ccccc1C2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
PTGS2 P35354 1/20 0.39
KDM4E B2RXH2 5/20 0.39
RAB9A P51151 3/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 5/20 0.38
MAPT P10636 5/20 0.38
GAA P10253 2/20 0.38
NPC1 O15118 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CASP3 P42574 1/20 0.38
CASP6 P55212 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
LMNA P02545 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216641 0.78 KDM4E (0.32) PTGS2KDM4ERAB9AALDH1A1MAPT
SCHEMBL4723228 0.74 PTGS2 (0.48) MEN1KMT2ACRHBPCRHR2PTGS2
SCHEMBL7984438 0.73 MAPT (0.56) MEN1KMT2ACRHBPCRHR2PTGS2
SCHEMBL218359 0.72 KDM4E (0.37) MEN1KMT2ACRHBPCRHR2PTGS2
SCHEMBL218437 0.70 ALDH1A1 (0.38) MEN1KMT2AKDM4ERAB9AALDH1A1
SCHEMBL2114697 0.70 GABRP (0.31) RAB9ANPC1
SCHEMBL8162708 0.70 ALDH1A1 (0.42) MEN1KMT2AKDM4ERAB9AMAPK1
SCHEMBL29672082 0.68 LMNA (0.50) MEN1KMT2APTGS2KDM4ERAB9A
SCHEMBL15522528 0.67 KDM4E (0.38) MEN1KMT2APTGS2KDM4ERAB9A
SCHEMBL2958343 0.67 RAB9A (0.38) MEN1KMT2AKDM4ERAB9AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1964860-B1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER TOSOH CORP (JP) 2017-07-05 EP disclosed
EP-1473323-B1 Polyethylene composition and process for producing same TOSOH CORP (JP) 2016-04-27 EP disclosed
US-8957159-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-02-17 US disclosed
US-20140066567-A1 Multiple Catalyst System for Olefin Polymerization and Polymers Produced Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2014-03-06 US disclosed
US-8563647-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-10-22 US disclosed
EP-1620479-B1 POLYOLEFIN ADHESIVE COMPOSITIONS AND ARTICLES MADE THEREFROM EXXONMOBIL CHEM PATENTS INC (US) 2013-07-24 EP disclosed
EP-1558655-B1 MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEM PATENTS INC (US) 2012-08-29 EP disclosed
US-20120095157-A1 Multiple Catalyst System For Olefin Polymerization And Polymers Produced Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2012-04-19 US disclosed
US-8088867-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-01-03 US disclosed
US-8071687-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-12-06 US disclosed
US-7678866-B2 Polyethylene composition and process for producing same TOSOH CORPORATION (JP) 2010-03-16 US disclosed
US-20090137755-A1 ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER TOSOH CORPORATION (JP) 2009-05-28 US disclosed
US-7524910-B2 Polyolefin adhesive compositions and articles made therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-04-28 US disclosed
US-20090069475-A1 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2009-03-12 US disclosed
EP-1964860-A1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER Tosoh Corporation (JP) 2008-09-03 EP disclosed
US-20070293640-A1 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2007-12-20 US disclosed
US-7294681-B2 Mutliple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-13 US disclosed
US-7223822-B2 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-29 US disclosed
EP-1473323-A1 Polyethylene composition and process for producing same Tosoh Corporation (JP) 2004-11-03 EP disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed