SCHEMBL21843451

SCHEMBL21843451

N#Cc1ccc(C(=O)c2ccc(N3c4ccccc4Oc4ccccc43)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 5/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
MMP1 P03956 1/20 0.39
PGR P06401 1/20 0.39
ELANE P08246 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19344969 0.88 ELANE (0.42) PGRELANEPOLB
SCHEMBL30874549 0.88 P2RX4 (0.50) P2RX4
SCHEMBL17851140 0.88 P2RX4 (0.50) P2RX4
SCHEMBL17850889 0.88 P2RX4 (0.50) P2RX4
SCHEMBL17879153 0.85 P2RX4 (0.56) P2RX4
SCHEMBL19344963 0.84 PGR (0.40) PGRELANEPOLB
SCHEMBL17851082 0.84 P2RX4 (0.46) P2RX4
SCHEMBL21843450 0.81 ALDH1A1 (0.48) P2RX4
SCHEMBL17851088 0.81 L3MBTL1 (0.50) P2RX4
SCHEMBL21843452 0.81 NPC1 (0.46) P2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10593888-B2 Polycyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10593888-B2 Polycyclic compound and organic light-emitting device including the same CRY1, PPOX, CRY2 P2RX4 1781/4885CA1 3180/4885CA2 3550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.