SCHEMBL2186122

SCHEMBL2186122

CC(=S)C(=S)n1ccnc1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 3/20 0.37
HSD17B10 Q99714 2/20 0.37
NFKB1 P19838 1/20 0.37
QPCTL Q9NXS2 1/20 0.37
CYP19A1 P11511 1/20 0.33
CYP3A4 P08684 2/20 0.32
BAZ2B Q9UIF8 1/20 0.32
MAPT P10636 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7812595 0.85 QPCT (0.38) QPCTHSD17B10NFKB1QPCTLCYP19A1
SCHEMBL762773 0.81
SCHEMBL4267268 0.75
SCHEMBL25270 0.75 QPCT (0.38) QPCTHSD17B10NFKB1QPCTLCYP19A1
SCHEMBL28055211 0.73 QPCT (0.36) QPCTHSD17B10NFKB1QPCTLCYP19A1
SCHEMBL27889965 0.73
SCHEMBL255373 0.73
SCHEMBL13685027 0.73
SCHEMBL411098 0.73
SCHEMBL8296674 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12194448-B2 Catalysts for the transformation of carbon dioxide and glycerol to formic acid and lactic acid and methods of making the same THE GEORGE WASHINGTON UNIVERSITY (US) 2025-01-14 US claimed
US-20200171474-A1 CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME THE GEORGE WASHINGTON UNIVERSITY 2020-06-04 US claimed
WO-2018213821-A1 CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME THE GEORGE WASHINGTON UNIVERSITY (US) 2018-11-22 WO claimed
WO-2008082224-A1 WATER-SOLUBLE PHOTOINITIATORS INKTEC CO., LTD. (KR) 2008-07-10 WO claimed
US-12194448-B2 Catalysts for the transformation of carbon dioxide and glycerol to formic acid and lactic acid and methods of making the same THE GEORGE WASHINGTON UNIVERSITY (US) 2025-01-14 US disclosed
US-20200171474-A1 CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME THE GEORGE WASHINGTON UNIVERSITY 2020-06-04 US disclosed
WO-2018213821-A1 CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME THE GEORGE WASHINGTON UNIVERSITY (US) 2018-11-22 WO disclosed
US-20150200422-A1 ELECTROLYTE ADDITIVE FOR LITHIUM BATTERY, ELECTROLYTE INCLUDING THE SAME, AND LITHIUM BATTERY INCLUDING THE ELECTROLYTE SAMSUNG SDI CO., LTD. (KR) 2015-07-16 US disclosed
US-20130005739-A1 PHARMACEUTICAL PREPARATIONS COMPRISING A COS RELEASING COMPOUND LUDWIG BOLTZMANN CLUSTER FUER KARDIOVASKULAERE FORSCHUNG (AT) 2013-01-03 US disclosed
EP-2343063-A1 Pharmaceutical preparations comprising a COS releasing compound Universität Wien (AT) 2011-07-13 EP disclosed
WO-2008082224-A1 WATER-SOLUBLE PHOTOINITIATORS INKTEC CO., LTD. (KR) 2008-07-10 WO disclosed
WO-2004101530-A1 A METHOD FOR PRODUCING DIVERSE SET OF DITHIOATE COMPOUNDS BIOORGANICS & APPLIED MATERIALS PVT LIMITED (IN) 2004-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12194448-B2 Catalysts for the transformation of carbon dioxide and glycerol to formic acid and lactic acid and methods of making the same MLX, LDHA, CA2 QPCT 1318/4885HSD17B10 299/4885NFKB1 4761/4885
US-20130005739-A1 PHARMACEUTICAL PREPARATIONS COMPRISING A COS RELEASING COMPOUND VIP, CRH, ADCYAP1R1 QPCT 1029/4885HSD17B10 537/4885NFKB1 1840/4885
US-20200171474-A1 CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME MLX, LDHA, CA2 QPCT 1318/4885HSD17B10 299/4885NFKB1 4761/4885
US-20150200422-A1 ELECTROLYTE ADDITIVE FOR LITHIUM BATTERY, ELECTROLYTE INCLUDING THE SAME, AND LITHIUM BATTERY INCLUDING THE ELECTROLYTE CLIC1, LAGE3, LRRK2 QPCT 4493/4885HSD17B10 330/4885NFKB1 2282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.