Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186625 | 0.82 | MAPT (0.56) | LMNAALOX15TSHRMAPK1ALDH1A1 | |
| SCHEMBL2186974 | 0.80 | CACNA2D1 (0.48) | LMNAALOX15TSHRMAPK1ALDH1A1 | |
| SCHEMBL27679675 | 0.80 | LMNA (0.50) | LMNAALOX15TSHRMAPK1ALDH1A1 | |
| SCHEMBL2188722 | 0.78 | KDM4E (0.57) | LMNAALOX15TSHRMAPK1ALDH1A1 | |
| SCHEMBL2188442 | 0.78 | NPC1 (0.47) | LMNAALOX15TSHRMAPK1ALDH1A1 | |
| SCHEMBL2187333 | 0.76 | MAPT (0.51) | LMNAALOX15TSHRALDH1A1MAPT | |
| SCHEMBL2186441 | 0.76 | L3MBTL1 (0.58) | LMNAALOX15TSHRMAPK1ALDH1A1 | |
| SCHEMBL2187707 | 0.76 | MLNR (0.41) | LMNAALOX15TSHRMAPK1ALDH1A1 | |
| SCHEMBL2186946 | 0.76 | LMNA (0.46) | LMNAALOX15TSHRMAPK1ALDH1A1 | |
| SCHEMBL2187555 | 0.75 | MEN1 (0.50) | LMNACYP2D6MAPTPKMALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101031567-B | Novel heterocyclic NF-kB inhibitors | 4SC Corp.,Ltd. (DE) | 2011-12-21 | — | — | CN | disclosed |
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |
| CN-101031567-A | Novel heterocyclic NF-kB inhibitors | 4SC AG (DE) | 2007-09-05 | — | — | CN | disclosed |