SCHEMBL11118957

SCHEMBL11118957

Cc1ccc2c(c1Nc1ccccc1)C1(OC2=O)c2ccccc2Oc2c(NC3(C)CCCCC3(C)C)cccc21

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2186537 0.81 FTO (0.40) CXCR2
SCHEMBL7772047 0.75 MAPT (0.38)
SCHEMBL6535261 0.73 LMNA (0.43)
SCHEMBL10637360 0.73 RAPGEF4 (0.39)
SCHEMBL10885744 0.71 FTO (0.39)
SCHEMBL10633830 0.70 PTGS2 (0.40)
SCHEMBL28247843 0.70 FTO (0.55) CXCR2
SCHEMBL10634017 0.69 LMNA (0.41)
SCHEMBL10884503 0.69 LMNA (0.40)
SCHEMBL2301733 0.68 MAPT (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0112710-A1 Fluoran derivatives KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1984-07-04 EP disclosed