SCHEMBL218707

SCHEMBL218707

COCCCOc1cc(CC(C=O)C(C)C)ccc1OC

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 19/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14777605 1.00 REN (0.47) REN
SCHEMBL2568835 0.86 LDHA (0.55)
SCHEMBL31666050 0.86 LDHA (0.55)
SCHEMBL2575301 0.86 LDHA (0.55)
SCHEMBL253884 0.86 FOS (0.49) REN
SCHEMBL3914703 0.85 REN (0.52) REN
SCHEMBL3912919 0.85 REN (0.52) REN
SCHEMBL2438095 0.85 REN (0.47) REN
SCHEMBL220393 0.83 MEN1 (0.47) REN
SCHEMBL14114916 0.82 ALOX15 (0.55) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9346745-B2 Process for producing Aliskiren CHEMO IBERICA, S.A. (ES) 2016-05-24 US claimed
EP-2576500-A2 PROCESS FOR PRODUCING ALISKIREN Chemo Iberica, S.A. (ES) 2013-04-10 EP claimed
US-20130071899-A1 Process for Producing Aliskiren CHEMO IBERICA, S.A. (ES) 2013-03-21 US claimed
US-8088954-B2 Preparation of a saturated aldehyde DSM IP ASSETS B.V. (NL) 2012-01-03 US claimed
WO-2011151442-A2 PROCESS FOR PRODUCING ALISKIREN CHEMO IBERICA, S.A. (ES) 2011-12-08 WO claimed
CN-101801903-A Preparation of a saturated aldehyde DSM IP ASSETS BV 2010-08-11 CN claimed
US-20100197972-A1 PREPARATION OF A SATURATED ALDEHYDE DSM IP ASSETS B.V. (NL) 2010-08-05 US claimed
EP-2173696-A1 PREPARATION OF A SATURATED ALDEHYDE DSM IP Assets B.V. (NL) 2010-04-14 EP claimed
WO-2009007461-A1 PREPARATION OF A SATURATED ALDEHYDE DSM IP ASSETS B.V. (NL) 2009-01-15 WO claimed
US-9346745-B2 Process for producing Aliskiren CHEMO IBERICA, S.A. (ES) 2016-05-24 US disclosed
US-20130252288-A1 ENANTIOSELECTIVE REDUCTION DSM IP ASSETS B.V. (NL) 2013-09-26 US disclosed
US-20130071899-A1 Process for Producing Aliskiren CHEMO IBERICA, S.A. (ES) 2013-03-21 US disclosed
US-8088954-B2 Preparation of a saturated aldehyde DSM IP ASSETS B.V. (NL) 2012-01-03 US disclosed
US-8088955-B2 Alpha-substituted α,β-unsaturated E- or Z-aldehydes, use thereof, and processes for their preparation α,β DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO. KG (AT) 2012-01-03 US disclosed
CN-101801903-A Preparation of a saturated aldehyde DSM IP ASSETS BV 2010-08-11 CN disclosed
US-20100197972-A1 PREPARATION OF A SATURATED ALDEHYDE DSM IP ASSETS B.V. (NL) 2010-08-05 US disclosed
EP-2173696-A1 PREPARATION OF A SATURATED ALDEHYDE DSM IP Assets B.V. (NL) 2010-04-14 EP disclosed
EP-2171077-A2 ENANTIOSELECTIVE REDUCTION DSM IP Assets B.V. (NL) 2010-04-07 EP disclosed
WO-2009007460-A2 ENANTIOSELECTIVE REDUCTION DSM IP ASSETS B.V. (NL) 2009-01-15 WO disclosed
WO-2009007461-A1 PREPARATION OF A SATURATED ALDEHYDE DSM IP ASSETS B.V. (NL) 2009-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100197972-A1 PREPARATION OF A SATURATED ALDEHYDE H1-0, F9, HRH4 REN 112/4885
US-20130071899-A1 Process for Producing Aliskiren REN, AGTR1, AGTR2 REN 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.