Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | DNM1L | O00429 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8852641 | 0.80 | SMN1; SMN2 (0.46) | DNM1LALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10136897 | 0.80 | L3MBTL1 (0.49) | LMNADNM1LALDH1A1TSHRKDM4E | |
| SCHEMBL20548151 | 0.79 | SMN1; SMN2 (0.49) | DNM1LALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7181442 | 0.79 | SMN1; SMN2 (0.45) | DNM1LALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL1436131 | 0.79 | SMN1; SMN2 (0.49) | DNM1LALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2563583 | 0.75 | ALDH1A1 (0.45) | LMNADNM1LALDH1A1TSHRKDM4E | |
| SCHEMBL7427898 | 0.72 | LMNA (0.40) | LMNAALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL21875350 | 0.72 | DNM1L (0.75) | DNM1L | |
| SCHEMBL13634188 | 0.72 | DNM1L (0.49) | LMNADNM1L | |
| SCHEMBL19051356 | 0.71 | SMN1; SMN2 (0.50) | LMNAALDH1A1TSHRKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168080-B2 | Dynamin-1-like protein inhibitors | MITOBRIDGE, INC. (US) | 2021-11-09 | — | — | US | disclosed |
| US-11168080-B2 | Dynamin-1-like protein inhibitors | MITOBRIDGE, INC. (US) | 2021-11-09 | — | — | US | disclosed |
| US-20200131172-A1 | DYNAMIN-1-LIKE PROTEIN INHIBITORS | Astellas Engineered Small Molecules US, Incorporated | 2020-04-30 | — | — | US | disclosed |
| US-20200131172-A1 | DYNAMIN-1-LIKE PROTEIN INHIBITORS | Astellas Engineered Small Molecules US, Incorporated | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168080-B2 | Dynamin-1-like protein inhibitors | DNM1L, DNM1, DNM2 | LMNA 2627/4885DNM1L 1/4885ALDH1A1 4737/4885 |
| US-20200131172-A1 | DYNAMIN-1-LIKE PROTEIN INHIBITORS | DNM1L, DNM1, DNM2 | LMNA 2627/4885DNM1L 1/4885ALDH1A1 4737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.