Sugi Predict

Sugi Predict / Compounds / SCHEMBL2187799

SCHEMBL2187799

SCHEMBL2187799

Cc1ccccc1-c1ccc(-c2ccccc2)nc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ENPP3 O14638 1/20 0.51
▸ ENPP1 P22413 1/20 0.51
▸ LDHA P00338 2/20 0.49
▸ CYP11B1 P15538 2/20 0.48
▸ CYP11B2 P19099 2/20 0.48
▸ HPGDS O60760 1/20 0.47
▸ BAZ2B Q9UIF8 1/20 0.46
▸ ALOX5AP P20292 1/20 0.46
▸ FEN1 P39748 1/20 0.46
▸ NPC1 O15118 2/20 0.43
▸ RAB9A P51151 2/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ HSD17B1 P14061 1/20 0.43
▸ HSD17B2 P37059 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ KDR P35968 2/20 0.43
▸ LCK P06239 1/20 0.43
▸ JAK3 P52333 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21742836 0.93 LDHA (0.46) ENPP3ENPP1LDHACYP11B1CYP11B2
SCHEMBL21742855 0.86 LDHA (0.44) ENPP3ENPP1LDHACYP11B1CYP11B2
SCHEMBL16526672 0.85 IDO1 (0.44) ENPP3ENPP1LDHACYP11B1CYP11B2
SCHEMBL21742854 0.82 ENPP3 (0.42) ENPP3ENPP1LDHACYP11B1CYP11B2
SCHEMBL19794388 0.82 LDHA (0.46) LDHACYP11B1CYP11B2HPGDSBAZ2B
SCHEMBL3853572 0.81 CYP11B1 (0.48) LDHACYP11B1CYP11B2HPGDSBAZ2B
SCHEMBL23956291 0.81 LDHA (0.42) ENPP3ENPP1LDHACYP11B1CYP11B2
SCHEMBL16622251 0.81 NPC1 (0.49) ENPP3ENPP1LDHACYP11B1CYP11B2
SCHEMBL18015574 0.81 LDHA (0.52) LDHACYP11B1CYP11B2HPGDSBAZ2B
SCHEMBL20405241 0.81 ENPP3 (0.58) ENPP3ENPP1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12127470-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-10-22 — — US disclosed
EP-4223854-A2 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2023-08-09 — — EP disclosed
EP-4223854-A2 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2023-08-09 — — EP disclosed
EP-3399005-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2023-05-31 — — EP disclosed
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-23 — — US disclosed
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-23 — — US disclosed
US-11482685-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-10-25 — — US disclosed
EP-3858945-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2021-08-04 — — EP disclosed
US-20210074931-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-11 — — US disclosed
US-20210074931-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-11 — — US disclosed
US-20110227049-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2011-09-22 — — US disclosed
US-20110227049-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2011-09-22 — — US disclosed
EP-2342305-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2011-07-13 — — EP disclosed
US-20100141127-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-06-10 — — US disclosed
US-20100141127-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-06-10 — — US disclosed
WO-2010056669-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-05-20 — — WO disclosed
WO-2010028151-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 — — WO disclosed
WO-2010028151-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 — — WO disclosed
WO-2010027583-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 — — WO disclosed
WO-2010027583-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100141127-A1 PHOSPHORESCENT EMITTERS PAICS, TYMP, NUDT1 ENPP3 74/4885ENPP1 96/4885LDHA 1020/4885
US-12127470-B2 Organic electroluminescent materials and devices SOD1, CLTB, L1CAM ENPP3 2621/4885ENPP1 4283/4885LDHA 163/4885
US-20210074931-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EML4, MCM4, KCNMB4 ENPP3 3273/4885ENPP1 4271/4885LDHA 207/4885
US-20110227049-A1 PHOSPHORESCENT MATERIALS PPIP5K2, PAICS, IP6K1 ENPP3 261/4885ENPP1 721/4885LDHA 1478/4885
US-11482685-B2 Organic electroluminescent materials and devices EML4, MCM4, KCNMB4 ENPP3 3273/4885ENPP1 4271/4885LDHA 207/4885
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, CLTB, L1CAM ENPP3 2621/4885ENPP1 4283/4885LDHA 163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.