SCHEMBL21882315

SCHEMBL21882315

CC(C)OC1CC2OCC(O)C2O1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21882318 0.80 THRB (0.32) THRBLMNA
SCHEMBL23896835 0.72 THRB (0.31) THRBLMNA
SCHEMBL220519 0.71 MAPT (0.53) THRBLMNA
SCHEMBL8283547 0.71 THRB (0.44) THRBLMNA
SCHEMBL19477926 0.67 ATP1A1 (0.31)
SCHEMBL20912079 0.66 THRB (0.54) THRBLMNA
SCHEMBL21097627 0.66 THRB (0.54) THRBLMNA
SCHEMBL24137980 0.66 THRB (0.54) THRBLMNA
SCHEMBL18959379 0.66 THRB (0.54) THRBLMNA
SCHEMBL1897888 0.66 THRB (0.54) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220017566-A1 TERPINOID DERIVATIVES AND USES THEREOF FRONTHERA U.S. PHARMACEUTICALS LLC 2022-01-20 US disclosed
WO-2020068689-A1 TERPINOID DERIVATIVES AND USES THEREOF FRONTHERA U.S. PHARMACEUTICALS LLC (US) 2020-04-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220017566-A1 TERPINOID DERIVATIVES AND USES THEREOF KEAP1, PTGES, GSTK1 THRB 453/4885LMNA 2033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.