SCHEMBL21885348

SCHEMBL21885348

CCOC(=O)c1cc2ccc(Cl)cc2cn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.50
GABRA2 P47869 12/20 0.48
GABRB2 P47870 12/20 0.48
GABRP O00591 5/20 0.48
GABRD O14764 5/20 0.48
GABRA1 P14867 5/20 0.48
GABRB1 P18505 5/20 0.48
GABRG2 P18507 5/20 0.48
GABRB3 P28472 5/20 0.48
GABRA5 P31644 5/20 0.48
GABRA3 P34903 5/20 0.48
GABRA4 P48169 5/20 0.48
GABRE P78334 5/20 0.48
GABRA6 Q16445 5/20 0.48
GABRG1 Q8N1C3 5/20 0.48
GABRG3 Q99928 5/20 0.48
GABRQ Q9UN88 5/20 0.48
CYP1A2 P05177 1/20 0.47
MAPT P10636 3/20 0.46
LMNA P02545 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21885738 0.94 ALOX15 (0.50) ALOX15GABRA2GABRB2GABRPGABRD
SCHEMBL740718 0.84 LCK (0.55) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL4538233 0.83 ALDH1A1 (0.53) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL30712301 0.82 GABRA1 (0.59) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL2201127 0.82 GABRA1 (0.59) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL30712292 0.82 GABRA1 (0.59) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL22395353 0.81 GABRA1 (0.49) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL31235495 0.79 CYP1A2 (0.51) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL25982216 0.79 NPC1 (0.41) MAPTNPC1SMN1; SMN2
SCHEMBL2414269 0.79 CYP1A2 (0.51) GABRA2GABRB2GABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737355-B2 Organic electroluminescence device and amine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-22 US disclosed
US-20200106022-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200106022-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE MAOA, PNMT, TPH1 ALOX15 214/4885GABRA2 4000/4885GABRB2 4232/4885
US-11737355-B2 Organic electroluminescence device and amine compound for organic electroluminescence device MAOA, PNMT, TPH1 ALOX15 214/4885GABRA2 4000/4885GABRB2 4232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.