Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21888597 | 0.79 | HTR2A (0.31) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL21887773 | 0.79 | PTGS2 (0.34) | HTR2AHTR2CHTR2BOPRM1OPRD1 | |
| SCHEMBL21888596 | 0.78 | HTR2A (0.30) | HTR2AHTR2CHTR2B | |
| SCHEMBL21887739 | 0.74 | NR1H2 (0.53) | — | |
| SCHEMBL21887870 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL31351756 | 0.65 | MEN1 (0.43) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL24185333 | 0.64 | GABRG2 (0.44) | HTR2AHTR2CHTR2BOPRM1OPRD1 | |
| SCHEMBL4419838 | 0.63 | PBRM1 (0.50) | HTR2AHTR2CHTR2BOPRM1OPRD1 | |
| SCHEMBL31426351 | 0.61 | HTR2B (0.38) | HTR2AHTR2CHTR2BOPRM1OPRD1 | |
| SCHEMBL13437405 | 0.60 | HTR2B (0.40) | HTR2AHTR2CHTR2BOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626712-A2 | LIVER X RECEPTOR (LXR) MODULATORS | Ellora Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |