Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21887773 | 0.86 | PTGS2 (0.34) | HTR2AHTR2CHTR2B | |
| SCHEMBL21888597 | 0.79 | HTR2A (0.31) | HTR2AHTR2CHTR2B | |
| SCHEMBL21887738 | 0.78 | HTR2A (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL21888599 | 0.76 | NR1H2 (0.44) | — | |
| SCHEMBL21888601 | 0.74 | NR1H2 (0.42) | — | |
| SCHEMBL21887870 | 0.72 | ALDH1A1 (0.41) | — | |
| SCHEMBL31351756 | 0.62 | MEN1 (0.43) | HTR2AHTR2CHTR2B | |
| SCHEMBL24185333 | 0.61 | GABRG2 (0.44) | HTR2AHTR2CHTR2B | |
| SCHEMBL4419838 | 0.61 | PBRM1 (0.50) | HTR2AHTR2CHTR2B | |
| SCHEMBL3471347 | 0.60 | RXRA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626712-A2 | LIVER X RECEPTOR (LXR) MODULATORS | Ellora Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |