Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2189374 | 1.00 | RAB9A (0.53) | RAB9AKDM4EALDH1A1HTR2APRMT1 | |
| SCHEMBL2770961 | 0.87 | KDM4E (0.55) | RAB9AKDM4EALDH1A1HTR2APRMT1 | |
| SCHEMBL2770965 | 0.87 | KDM4E (0.55) | RAB9AKDM4EALDH1A1HTR2APRMT1 | |
| SCHEMBL11379451 | 0.84 | RAB9A (0.41) | RAB9AKDM4EALDH1A1HTR2APRMT1 | |
| SCHEMBL3299029 | 0.84 | RAB9A (0.50) | RAB9AKDM4EALDH1A1HTR2APRMT1 | |
| SCHEMBL3299030 | 0.84 | RAB9A (0.50) | RAB9AKDM4EALDH1A1HTR2APRMT1 | |
| SCHEMBL11597360 | 0.83 | PRMT1 (0.55) | RAB9AKDM4EALDH1A1HTR2APRMT1 | |
| SCHEMBL11597357 | 0.83 | PRMT1 (0.55) | RAB9AKDM4EALDH1A1HTR2APRMT1 | |
| SCHEMBL14275030 | 0.83 | KDM4E (0.52) | RAB9AKDM4EALDH1A1HTR2APRMT1 | |
| (Z)-1,2-Diphenylethene SCHEMBL9179151 | 0.82 | RELA (0.52) | RAB9AKDM4EALDH1A1MAOBRELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399594-B2 | Blocked-isocyanate silicone resins | DOW CORNING CORPORATION (US) | 2013-03-19 | — | — | US | disclosed |
| EP-2351738-A1 | PROCESS FOR PRODUCING 1-SUBSTITUTED TRANS-4-(SUBSTITUTED AMINO)PIPERIDIN-3-OL | Sumitomo Chemical Company, Limited (JP) | 2011-08-03 | — | — | EP | disclosed |
| US-20110172431-A1 | PROCESS FOR PRODUCING 1-SUBSTITUTED TRANS-4-(SUBSTITUTED AMINO) PIPERIDIN-3-OL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20100093902-A1 | Blocked-Isocyanate Silicone Resins | DOW CORNING CORPORATION | 2010-04-15 | — | — | US | disclosed |
| EP-2102286-A1 | BLOCKED ISOCYANATE SILICONE RESINS | Dow Corning Corporation (US) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008088492-A1 | BLOCKED ISOCYANATE SILICONE RESINS | DOW CORNING CORPORATRION (US) | 2008-07-24 | — | — | WO | disclosed |
| US-20070167587-A1 | Process for producing polymer with functional end | KURARAY CO., LTD. (JP) | 2007-07-19 | — | — | US | disclosed |
| EP-1420008-B1 | Composition, in particular cosmetic, comprising a secondary or tertiary amine | OREAL (FR) | 2006-12-20 | — | — | EP | disclosed |
| EP-1721912-A1 | PROCESS FOR PRODUCING POLYMER WITH FUNCTIONAL END | KURARAY CO., LTD. (JP) | 2006-11-15 | — | — | EP | disclosed |
| US-20040143009-A1 | Amines, uses thereof | L'OREAL (FR) | 2004-07-22 | — | — | US | disclosed |
| EP-1420008-A1 | Composition, in particular cosmetic, comprising a secondary or tertiary amine | L'OREAL (FR) | 2004-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040143009-A1 | Amines, uses thereof | COL14A1, FBL, CUTA | RAB9A 2070/4885KDM4E 1327/4885ALDH1A1 2574/4885 |
| US-20110172431-A1 | PROCESS FOR PRODUCING 1-SUBSTITUTED TRANS-4-(SUBSTITUTED AMINO) PIPERIDIN-3-OL | TEAD4, TEAD3, TEAD2 | RAB9A 417/4885KDM4E 1125/4885ALDH1A1 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.