SCHEMBL2189374

SCHEMBL2189374

CCNCC=Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.53
KDM4E B2RXH2 1/20 0.49
ALDH1A1 P00352 1/20 0.46
HTR2A P28223 3/20 0.46
PRMT1 Q99873 1/20 0.45
MAOB P27338 2/20 0.44
IDO1 P14902 2/20 0.44
PAM P19021 1/20 0.44
RELA Q04206 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2189373 1.00 RAB9A (0.53) RAB9AKDM4EALDH1A1HTR2APRMT1
SCHEMBL2770961 0.87 KDM4E (0.55) RAB9AKDM4EALDH1A1HTR2APRMT1
SCHEMBL2770965 0.87 KDM4E (0.55) RAB9AKDM4EALDH1A1HTR2APRMT1
SCHEMBL11379451 0.84 RAB9A (0.41) RAB9AKDM4EALDH1A1HTR2APRMT1
SCHEMBL3299029 0.84 RAB9A (0.50) RAB9AKDM4EALDH1A1HTR2APRMT1
SCHEMBL3299030 0.84 RAB9A (0.50) RAB9AKDM4EALDH1A1HTR2APRMT1
SCHEMBL11597360 0.83 PRMT1 (0.55) RAB9AKDM4EALDH1A1HTR2APRMT1
SCHEMBL11597357 0.83 PRMT1 (0.55) RAB9AKDM4EALDH1A1HTR2APRMT1
SCHEMBL14275030 0.83 KDM4E (0.52) RAB9AKDM4EALDH1A1HTR2APRMT1
(Z)-1,2-Diphenylethene SCHEMBL9179151 0.82 RELA (0.52) RAB9AKDM4EALDH1A1MAOBRELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4246355-A ACTIVATION OF AN INNER POLYMER MATRIX IMPREGNATED WITH FERROMAGNETIC MATERIAL, GRAFT POLYMERIZATION OF OUTER SHELL ICI AUSTRALIA LIMITED (AU) 1981-01-20 US claimed
US-20230033703-A1 POLYMER COMPOSITION PRODUCTION METHOD ENEOS MATERIALS CORPORATION (JP) 2023-02-02 US disclosed
US-8399594-B2 Blocked-isocyanate silicone resins DOW CORNING CORPORATION (US) 2013-03-19 US disclosed
CN-101611098-B Blocked isocyanate silicone resins DOW CORNING INC 2011-10-26 CN disclosed
EP-2351738-A1 PROCESS FOR PRODUCING 1-SUBSTITUTED TRANS-4-(SUBSTITUTED AMINO)PIPERIDIN-3-OL Sumitomo Chemical Company, Limited (JP) 2011-08-03 EP disclosed
US-20110172431-A1 PROCESS FOR PRODUCING 1-SUBSTITUTED TRANS-4-(SUBSTITUTED AMINO) PIPERIDIN-3-OL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-14 US disclosed
US-20100093902-A1 Blocked-Isocyanate Silicone Resins DOW CORNING CORPORATION 2010-04-15 US disclosed
CN-101611098-A Blocked isocyanate silicone resins DOW CORNING CORPORATRION (US) 2009-12-23 CN disclosed
EP-2102286-A1 BLOCKED ISOCYANATE SILICONE RESINS Dow Corning Corporation (US) 2009-09-23 EP disclosed
WO-2008088492-A1 BLOCKED ISOCYANATE SILICONE RESINS DOW CORNING CORPORATRION (US) 2008-07-24 WO disclosed
EP-1420008-B1 Composition, in particular cosmetic, comprising a secondary or tertiary amine OREAL (FR) 2006-12-20 EP disclosed
EP-1721912-A1 PROCESS FOR PRODUCING POLYMER WITH FUNCTIONAL END KURARAY CO., LTD. (JP) 2006-11-15 EP disclosed
US-20040143009-A1 Amines, uses thereof L'OREAL (FR) 2004-07-22 US disclosed
EP-1420008-A1 Composition, in particular cosmetic, comprising a secondary or tertiary amine L'OREAL (FR) 2004-05-19 EP disclosed
EP-0764177-A1 CROSS-LINKED POLYMERS FOR REMOVING BILE SALTS FROM A PATIENT GELTEX PHARMACEUTICALS, INC. (US) 1997-03-26 EP disclosed
US-5075197-A Water based polymer dispersion FUJI PHOTO FILM CO., LTD. (JP) 1991-12-24 US disclosed
US-5015551-A Resin particles dispersed in a dielectric nonaqueous solvent for making printing plates or sheets FUJI PHOTO FILM CO., LTD. (JP) 1991-05-14 US disclosed
US-4734351-A DISPERSION OF POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1988-03-29 US disclosed
US-4473630-A Liquid developer comprising aminoalkyl styrene polymer for electrostatic images FUJI PHOTO FILM CO., LTD. (JP) 1984-09-25 US disclosed
US-4246355-A ACTIVATION OF AN INNER POLYMER MATRIX IMPREGNATED WITH FERROMAGNETIC MATERIAL, GRAFT POLYMERIZATION OF OUTER SHELL ICI AUSTRALIA LIMITED (AU) 1981-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040143009-A1 Amines, uses thereof COL14A1, FBL, CUTA RAB9A 2070/4885KDM4E 1327/4885ALDH1A1 2574/4885
US-20110172431-A1 PROCESS FOR PRODUCING 1-SUBSTITUTED TRANS-4-(SUBSTITUTED AMINO) PIPERIDIN-3-OL TEAD4, TEAD3, TEAD2 RAB9A 417/4885KDM4E 1125/4885ALDH1A1 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.