SCHEMBL219239

SCHEMBL219239

COc1cncc(B(O)OC(C)(C)C(C)(C)O)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 5/20 0.34
CYP11B2 P19099 5/20 0.34
ENPP2 Q13822 1/20 0.33
MKNK2 Q9HBH9 2/20 0.33
MKNK1 Q9BUB5 1/20 0.33
ROCK2 O75116 1/20 0.33
MAP4K4 O95819 1/20 0.33
PRKACA P17612 1/20 0.33
ROCK1 Q13464 1/20 0.33
DYRK1A Q13627 1/20 0.33
NTRK3 Q16288 1/20 0.33
PKN2 Q16513 1/20 0.33
CLK4 Q9HAZ1 1/20 0.33
STK17A Q9UEE5 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP1A1 P04798 1/20 0.32
CYP1B1 Q16678 1/20 0.32
SLC22A12 Q96S37 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1983047 0.82 ALDH1A1 (0.39) ENPP2CYP1A2CYP3A4CYP2C9CYP1A1
SCHEMBL458480 0.81 ATM (0.33)
SCHEMBL427184 0.81 HCAR2 (0.33)
SCHEMBL3660018 0.81 CHRNB2 (0.31) CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL584540 0.80 NPC1 (0.35) CYP1A2CYP3A4
SCHEMBL2067107 0.80 KDM4E (0.32)
SCHEMBL3102053 0.79 CYP1A1 (0.35) CYP11B1CYP11B2MKNK2MKNK1ROCK2
SCHEMBL13451428 0.79 ENPP2 (0.40) CYP11B1CYP11B2ENPP2MKNK2MKNK1
SCHEMBL2068547 0.78 CYP11B1 (0.35) CYP11B1CYP11B2
SCHEMBL3861990 0.78 CYP11B1 (0.33) CYP11B1CYP11B2ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4711359-A2 RESCORCINOLS, METHODS FOR THEIR MANUFACTURE, AND USES THEREOF Jazz Pharmaceuticals Research UK Limited (GB) 2026-03-18 EP disclosed
US-20250002475-A1 PIPERIDINE DERIVATIVES AS METTL3 INHIBITORS EPICS THERAPEUTICS (BE) 2025-01-02 US disclosed
US-12091400-B2 Piperidine derivatives as METTL3 inhibitors EPICS THERAPEUTICS (BE) 2024-09-17 US disclosed
US-20240270716-A1 PIPERIDINE DERIVATIVES AS METTL3 INHIBITORS EPICS THERAPEUTICS (BE) 2024-08-15 US disclosed
US-20240254066-A1 RESCORCINOLS, METHODS FOR THEIR MANUFACTURE, AND USES THEREOF JAZZ PHARMACEUTICALS RESEARCH UK LIMITED (GB) 2024-08-01 US disclosed
EP-4337315-A1 RESCORCINOLS, METHODS FOR THEIR MANUFACTURE, AND USES THEREOF GW Research Limited (GB) 2024-03-20 EP disclosed
CN-117396455-A Resorcinol, its manufacturing method and use 吉伟研究有限公司 2024-01-12 CN disclosed
CN-111808057-B Suzuki reaction using alpha-O-alkenyl sulfone as electrophile and application thereof 四川大学 2023-05-09 CN disclosed
CN-111808089-B Preparation method of drug eprogliflozin for treating diabetes or derivative thereof 四川大学华西医院 2023-04-11 CN disclosed
WO-2022238707-A1 RESCORCINOLS, METHODS FOR THEIR MANUFACTURE, AND USES THEREOF GW Research Limited (GB) 2022-11-17 WO disclosed
EP-1934216-A1 NAPHTHYRIDIN DERIVATIVES F.HOFFMANN-LA ROCHE AG (CH) 2008-06-25 EP disclosed
WO-2008073785-A2 PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND METHODS OF USE GENENTECH, INC. (US) 2008-06-19 WO disclosed
WO-2008070740-A1 PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND METHODS OF USE F.HOFFMANN-LA ROCHE AG (CH) 2008-06-12 WO disclosed
WO-2007148093-A1 ANTIBACTERIAL COMPOSITIONS PROLYSIS LTD. (GB) 2007-12-27 WO disclosed
US-20070197604-A1 Oxazole derivatives as histamine h3 receptor agents,preparation and therapeutic uses ELI LILLY AND COMPANY 2007-08-23 US disclosed
EP-1786790-A1 OXAZOLE DERIVATIVES AS HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES ELI LILLY AND COMPANY (US) 2007-05-23 EP disclosed
WO-2007039512-A1 NAPHTHYRIDIN DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2007-04-12 WO disclosed
US-20070078155-A1 Naphthyridin derivatives F. HOFFMANN-LA ROCHE AG (CH) 2007-04-05 US disclosed
US-20060111387-A1 ARYL SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY 2006-05-25 US disclosed
WO-2006019833-A1 OXAZOLE DERIVATIVES AS HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES ELI LILLY AND COMPANY (US) 2006-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070197604-A1 Oxazole derivatives as histamine h3 receptor agents,preparation and therapeutic uses HCRTR1, HRH3, HCRTR2 CYP11B1 1173/4885CYP11B2 1521/4885ENPP2 1856/4885
US-20070078155-A1 Naphthyridin derivatives GRM5, GRM3, GRM1 CYP11B1 1427/4885CYP11B2 1352/4885ENPP2 1206/4885
US-20240270716-A1 PIPERIDINE DERIVATIVES AS METTL3 INHIBITORS METTL3, METTL16, DIMT1 CYP11B1 3658/4885CYP11B2 4114/4885ENPP2 3519/4885
US-20250002475-A1 PIPERIDINE DERIVATIVES AS METTL3 INHIBITORS METTL3, METTL16, DIMT1 CYP11B1 3658/4885CYP11B2 4114/4885ENPP2 3519/4885
US-12091400-B2 Piperidine derivatives as METTL3 inhibitors METTL3, METTL16, DIMT1 CYP11B1 3658/4885CYP11B2 4114/4885ENPP2 3519/4885
US-20240254066-A1 RESCORCINOLS, METHODS FOR THEIR MANUFACTURE, AND USES THEREOF REN, CYP46A1, NQO1 CYP11B1 17/4885CYP11B2 18/4885ENPP2 317/4885
US-20060111387-A1 ARYL SUBSTITUTED IMIDAZOQUINOLINES IL2, IFNG, IRF3 CYP11B1 492/4885CYP11B2 334/4885ENPP2 1122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.