SCHEMBL219239

SCHEMBL219239

COc1cncc(B(O)OC(C)(C)C(C)(C)O)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP11B1 P15538 5/20 0.34
▸ CYP11B2 P19099 5/20 0.34
▸ ENPP2 Q13822 1/20 0.33
▸ MKNK2 Q9HBH9 2/20 0.33
▸ MKNK1 Q9BUB5 1/20 0.33
▸ ROCK2 O75116 1/20 0.33
▸ MAP4K4 O95819 1/20 0.33
▸ PRKACA P17612 1/20 0.33
▸ ROCK1 Q13464 1/20 0.33
▸ DYRK1A Q13627 1/20 0.33
▸ NTRK3 Q16288 1/20 0.33
▸ PKN2 Q16513 1/20 0.33
▸ CLK4 Q9HAZ1 1/20 0.33
▸ STK17A Q9UEE5 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ CYP1A1 P04798 1/20 0.32
▸ CYP1B1 Q16678 1/20 0.32
▸ SLC22A12 Q96S37 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1983047 0.82 ALDH1A1 (0.39) ENPP2CYP1A2CYP3A4CYP2C9CYP1A1
SCHEMBL427184 0.81 HCAR2 (0.33) —
SCHEMBL3660018 0.81 CHRNB2 (0.31) CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL458480 0.81 ATM (0.33) —
SCHEMBL2067107 0.80 KDM4E (0.32) —
SCHEMBL584540 0.80 NPC1 (0.35) CYP1A2CYP3A4
SCHEMBL3102053 0.79 CYP1A1 (0.35) CYP11B1CYP11B2MKNK2MKNK1ROCK2
SCHEMBL13451428 0.79 ENPP2 (0.40) CYP11B1CYP11B2ENPP2MKNK2MKNK1
SCHEMBL2068547 0.78 CYP11B1 (0.35) CYP11B1CYP11B2
SCHEMBL17651864 0.78 KDM4E (0.37) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4711359-A2 RESCORCINOLS, METHODS FOR THEIR MANUFACTURE, AND USES THEREOF Jazz Pharmaceuticals Research UK Limited (GB) 2026-03-18 — — EP disclosed
US-20250002475-A1 PIPERIDINE DERIVATIVES AS METTL3 INHIBITORS EPICS THERAPEUTICS (BE) 2025-01-02 — — US disclosed
US-12091400-B2 Piperidine derivatives as METTL3 inhibitors EPICS THERAPEUTICS (BE) 2024-09-17 — — US disclosed
US-20240270716-A1 PIPERIDINE DERIVATIVES AS METTL3 INHIBITORS EPICS THERAPEUTICS (BE) 2024-08-15 — — US disclosed
US-20240254066-A1 RESCORCINOLS, METHODS FOR THEIR MANUFACTURE, AND USES THEREOF JAZZ PHARMACEUTICALS RESEARCH UK LIMITED (GB) 2024-08-01 — — US disclosed
EP-4337315-A1 RESCORCINOLS, METHODS FOR THEIR MANUFACTURE, AND USES THEREOF GW Research Limited (GB) 2024-03-20 — — EP disclosed
CN-117396455-A Resorcinol, its manufacturing method and use 吉伟研究有限公司 2024-01-12 — — CN disclosed
CN-111808057-B Suzuki reaction using alpha-O-alkenyl sulfone as electrophile and application thereof 四川大学 2023-05-09 — — CN disclosed
CN-111808089-B Preparation method of drug eprogliflozin for treating diabetes or derivative thereof 四川大学华西医院 2023-04-11 — — CN disclosed
WO-2022238707-A1 RESCORCINOLS, METHODS FOR THEIR MANUFACTURE, AND USES THEREOF GW Research Limited (GB) 2022-11-17 — — WO disclosed
EP-1934216-A1 NAPHTHYRIDIN DERIVATIVES F.HOFFMANN-LA ROCHE AG (CH) 2008-06-25 — — EP disclosed
WO-2008073785-A2 PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND METHODS OF USE GENENTECH, INC. (US) 2008-06-19 — — WO disclosed
WO-2008070740-A1 PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND METHODS OF USE F.HOFFMANN-LA ROCHE AG (CH) 2008-06-12 — — WO disclosed
WO-2007148093-A1 ANTIBACTERIAL COMPOSITIONS PROLYSIS LTD. (GB) 2007-12-27 — — WO disclosed
US-20070197604-A1 Oxazole derivatives as histamine h3 receptor agents,preparation and therapeutic uses ELI LILLY AND COMPANY 2007-08-23 — — US disclosed
EP-1786790-A1 OXAZOLE DERIVATIVES AS HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES ELI LILLY AND COMPANY (US) 2007-05-23 — — EP disclosed
WO-2007039512-A1 NAPHTHYRIDIN DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2007-04-12 — — WO disclosed
US-20070078155-A1 Naphthyridin derivatives F. HOFFMANN-LA ROCHE AG (CH) 2007-04-05 — — US disclosed
US-20060111387-A1 ARYL SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY 2006-05-25 — — US disclosed
WO-2006019833-A1 OXAZOLE DERIVATIVES AS HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES ELI LILLY AND COMPANY (US) 2006-02-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070197604-A1 Oxazole derivatives as histamine h3 receptor agents,preparation and therapeutic uses HCRTR1, HRH3, HCRTR2 CYP11B1 1173/4885CYP11B2 1521/4885ENPP2 1856/4885
US-20070078155-A1 Naphthyridin derivatives GRM5, GRM3, GRM1 CYP11B1 1427/4885CYP11B2 1352/4885ENPP2 1206/4885
US-20240270716-A1 PIPERIDINE DERIVATIVES AS METTL3 INHIBITORS METTL3, METTL16, DIMT1 CYP11B1 3658/4885CYP11B2 4114/4885ENPP2 3519/4885
US-20250002475-A1 PIPERIDINE DERIVATIVES AS METTL3 INHIBITORS METTL3, METTL16, DIMT1 CYP11B1 3658/4885CYP11B2 4114/4885ENPP2 3519/4885
US-12091400-B2 Piperidine derivatives as METTL3 inhibitors METTL3, METTL16, DIMT1 CYP11B1 3658/4885CYP11B2 4114/4885ENPP2 3519/4885
US-20240254066-A1 RESCORCINOLS, METHODS FOR THEIR MANUFACTURE, AND USES THEREOF REN, CYP46A1, NQO1 CYP11B1 17/4885CYP11B2 18/4885ENPP2 317/4885
US-20060111387-A1 ARYL SUBSTITUTED IMIDAZOQUINOLINES IL2, IFNG, IRF3 CYP11B1 492/4885CYP11B2 334/4885ENPP2 1122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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