N6-Benzyladenosine

N6-Benzyladenosine

SCHEMBL219439

OC[C@H]1O[C@@H](n2cnc3c(NCc4ccccc4)ncnc32)C(O)C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 9/20 1.00
SLC29A1 Q99808 2/20 1.00
TP53 P04637 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
ADORA2A P29274 6/20 0.82
ADORA1 P30542 6/20 0.82
NFKB1 P19838 1/20 0.82
THPO P40225 1/20 0.82
TSHR P16473 1/20 0.82
ADORA2B P29275 1/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N6-Benzyladenosine SCHEMBL13966412 1.00 ADORA3 (1.00) ADORA3SLC29A1TP53TDP1ADORA2A
N6-Benzyladenosine SCHEMBL219438 1.00 ADORA3 (1.00) ADORA3SLC29A1TP53TDP1ADORA2A
N6-Benzyladenosine SCHEMBL20419317 1.00 ADORA3 (1.00) ADORA3SLC29A1TP53TDP1ADORA2A
N6-Benzyladenosine SCHEMBL15614834 1.00 ADORA3 (1.00) ADORA3SLC29A1TP53TDP1ADORA2A
N6-Benzyladenosine SCHEMBL472637 1.00 ADORA3 (1.00) ADORA3SLC29A1TP53TDP1ADORA2A
N6-Benzyladenosine SCHEMBL472635 1.00 ADORA3 (1.00) ADORA3SLC29A1TP53TDP1ADORA2A
N6-Benzyladenosine SCHEMBL23982413 1.00 ADORA3 (1.00) ADORA3SLC29A1TP53TDP1ADORA2A
N6-Benzyladenosine SCHEMBL20419282 1.00 ADORA3 (1.00) ADORA3SLC29A1TP53TDP1ADORA2A
N6-Benzyladenosine SCHEMBL3283829 1.00 ADORA3 (1.00) ADORA3SLC29A1TP53TDP1ADORA2A
N6-Benzyladenosine SCHEMBL30230333 1.00 ADORA3 (1.00) ADORA3SLC29A1TP53TDP1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8119614-B2 Substitution derivatives of N6-benzyladenosine, methods of their preparation, their use for preparation of drugs, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds USTAV EXPERIMENTALNI BOTANIKY AKADEMIE VED CESKE REPUBLIKY (CZ) 2012-02-21 US claimed
US-20090203638-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION VDF FUTURECEUTICALS, INC. (US) 2009-08-13 US claimed
US-20070161582-A1 Pharmaceutical compositions and methods for metabolic modulation VDF FUTURECEUTICALS 2007-07-12 US claimed
EP-1575973-A2 SUBSTITUTION DERIVATIVES OF N SP 6 SP -BENZYLADENOSINE, METHODS OF THEIR PREPARATION, THEIR USE FOR PREPARATION OF DRUGS, COSMETIC PREPARATIONS AND GROWTH REGULATORS, PHARMACEUTICAL PREPARATIONS, COSMETIC PREPARATIONS AND GROWTH REGULATORS CONTAINING THESE COMPOUNDS Ustav Experimentalni Botaniky Akademie ved Ceské Republiky (CZ) 2005-09-21 EP claimed
WO-2005020892-A2 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION MITOCHROMA RESEARCH, INC. (US) 2005-03-10 WO claimed
WO-2004058791-A2 SUBSTITUTION DERIVATIVES OF N6-BENZYLADENOSINE, METHODS OF THEIR PREPARATION, THEIR USE FOR PREPARATION OF DRUGS, COSMETIC PREPARATIONS AND GROWTH REGULATORS, PHARMACEUTICAL PREPARATIONS, COSMETIC PREPARATIONS AND GROWTH REGULATORS CONTAINING THESE COMPOUNDS USTAV EXPERIMENTALNI BOTANIKY AKADEMIE VED CESKE REPUBLIKY (CZ) 2004-07-15 WO claimed
EP-4747386-A1 DOUBLE-STRANDED OLIGONUCLEOTIDE AGENTS AND USES THEREOF Bisirna Therapeutics Pte. Ltd. (SG) 2026-05-27 EP disclosed
EP-4743089-A1 A3 ADENOSINE RECEPTOR LIGANDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH OCRL GENE DISFUNCTION Fondazione Telethon ETS (IT) 2026-05-20 EP disclosed
US-20260115218-A1 TREATMENT OF ADVANCED METASTATIC CANCER CAN-FITE BIOPHARMA LTD. (IL) 2026-04-30 US disclosed
US-20260014184-A1 ADENOSINE DERIVATIVES FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS AND CANCER UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) 2026-01-15 US disclosed
US-20250359548-A1 METHODS OF IMPROVING STRESS TOLERANCE, GROWTH AND YIELD IN PLANTS VALENT BIOSCIENCES LLC (US) 2025-11-27 US disclosed
US-20250345353-A1 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS ASTROCYTE PHARMACEUTICALS INC (US) 2025-11-13 US disclosed
EP-4633645-A1 ADENOSINE DERIVATIVES FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS AND CANCER University College Cardiff Consultants Limited (GB) 2025-10-22 EP disclosed
EP-0322242-B1 Adenosine derivatives GLAXO GROUP LTD (GB) 1998-04-01 EP disclosed
US-5688774-A ANTIINFLAMMATORY AGENTS, HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1997-11-18 US disclosed
EP-0755255-A1 TREATMENT OF TOXOPLASMOSIS UNIVERSITY OF ALABAMA, BIRMINGHAM RESEARCH FOUNDATION (US) 1997-01-29 EP disclosed
WO-1996018398-A1 TREATMENT OF TOXOPLASMOSIS THE UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION (US) 1996-06-20 WO disclosed
EP-0253962-B1 USE OF ADENOSINE DERIVATIVES AS ANTI-DEMENTIA AGENTS HOECHST JAPAN LIMITED (JP) 1993-03-24 EP disclosed
EP-0355825-A2 Viral treatment system Prendergast, Patrick T. (IE) 1990-02-28 EP disclosed
EP-0322242-A2 Adenosine derivatives GLAXO GROUP LIMITED (GB) 1989-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250345353-A1 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS TNNI3, CPT1B, TNNT2 ADORA3 778/4885SLC29A1 2267/4885TP53 4761/4885
US-20260014184-A1 ADENOSINE DERIVATIVES FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS AND CANCER ADRM1, ADORA1, ADORA2A ADORA3 8/4885SLC29A1 284/4885TP53 61/4885
US-20070161582-A1 Pharmaceutical compositions and methods for metabolic modulation GPR119, PRKAG2, PRKAG1 ADORA3 162/4885SLC29A1 710/4885TP53 2033/4885
US-20260115218-A1 TREATMENT OF ADVANCED METASTATIC CANCER ADORA2B, ADORA3, ADORA2A ADORA3 2/4885SLC29A1 299/4885TP53 400/4885
US-20090203638-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION GPR119, PRKAG2, GCKR ADORA3 153/4885SLC29A1 670/4885TP53 2134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.