Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21949126 | 0.74 | GABRA1 (0.48) | GABRA1SIGMAR1TUBB1PTGS2ALOX5 | |
| SCHEMBL17355686 | 0.70 | HTR1D (0.43) | PTGS2PTGS1 | |
| SCHEMBL21949129 | 0.70 | MEN1 (0.31) | — | |
| SCHEMBL564461 | 0.66 | GABRA1 (0.57) | GABRA1SIGMAR1TUBB1PTGS2ALOX5 | |
| SCHEMBL4197382 | 0.66 | CYP2C9 (0.46) | PTGS2ALDH1A1 | |
| SCHEMBL29642252 | 0.66 | ALDH1A1 (0.47) | GABRA1SIGMAR1TUBB1PTGS2ALOX5 | |
| SCHEMBL336067 | 0.66 | ALDH1A1 (0.47) | GABRA1SIGMAR1TUBB1PTGS2ALOX5 | |
| SCHEMBL26539900 | 0.64 | GABRA1 (0.51) | GABRA1SIGMAR1TUBB1PTGS2ALOX5 | |
| SCHEMBL28524299 | 0.64 | PTGS2 (0.42) | GABRA1SIGMAR1TUBB1PTGS2ALOX5 | |
| SCHEMBL27018581 | 0.63 | AKR1C3 (0.43) | PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640247-B1 | SYK INHIBITOR AND USE METHOD THEREFOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2022-01-12 | — | — | EP | disclosed |
| EP-3640247-A1 | SYK INHIBITOR AND USE METHOD THEREFOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-04-22 | — | — | EP | disclosed |