Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24181250 | 0.79 | VCP (0.46) | GABRA1SIGMAR1PTGS2TRPA1 | |
| SCHEMBL564461 | 0.77 | GABRA1 (0.57) | GABRA1SIGMAR1PTGS2PTGS1ALOX5 | |
| SCHEMBL336067 | 0.77 | ALDH1A1 (0.47) | GABRA1SIGMAR1PTGS2PTGS1ALOX5 | |
| SCHEMBL29642252 | 0.77 | ALDH1A1 (0.47) | GABRA1SIGMAR1PTGS2PTGS1ALOX5 | |
| SCHEMBL26539900 | 0.74 | GABRA1 (0.51) | GABRA1SIGMAR1PTGS2PTGS1ALOX5 | |
| SCHEMBL21949120 | 0.74 | GABRA1 (0.39) | GABRA1SIGMAR1PTGS2PTGS1ALOX5 | |
| SCHEMBL16958944 | 0.72 | GABRA1 (0.47) | GABRA1SIGMAR1PTGS2PTGS1ALOX5 | |
| SCHEMBL5231765 | 0.72 | GABRA1 (0.46) | GABRA1SIGMAR1PTGS2PTGS1ALOX5 | |
| SCHEMBL28684322 | 0.72 | GABRA1 (0.46) | GABRA1SIGMAR1PTGS2PTGS1ALOX5 | |
| SCHEMBL5229721 | 0.72 | GABRA1 (0.46) | GABRA1SIGMAR1PTGS2PTGS1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640247-A1 | SYK INHIBITOR AND USE METHOD THEREFOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-04-22 | — | — | EP | disclosed |